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J-GLOBAL ID：201802249124105206   Reference number：18A0287616

Evaluation of synthesized coumarin derivatives on aromatase inhibitory activity

アロマターゼ阻害活性に及ぼす合成したクマリン誘導体の評価【Powered by NICT】

Author (6)： Yamaguchi Yuki (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan) ,  Nishizono Naozumi (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan) ,  Kobayashi Daisuke (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan) ,  Yoshimura Teruki (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan) ,  Wada Keiji (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan) ,  Oda Kazuaki (School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan)
Material： Bioorganic & Medicinal Chemistry Letters  (Bioorg Med Chem Lett)
Volume： 27  Issue： 12  Page： 2645-2649  Publication year： 2017 
JST Material Number： W0248A  ISSN： 0960-894X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： In women across the world, the...

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Thesaurus term： *Aromatase ,  aromatase inhibitor ,  woman ,  breast tumor ,  Structure-Activity Relationship ,  substituent ,  Postmenopause ,  endocrine therapy ,  *Coumarins ,  *inhibitory activity
Semi thesaurus term： 阻害剤 ,  閉経前乳癌 , 【Automatic Indexing@JST】

Author keywords (8)： Breast cancer ,  Aromatase ,  CYP19 ,  Inhibitor ,  Coumarin ,  Pyridine ,  Thiazole ,  Oxazole

JST classification (2)： Structure-activity relationship of drugs  (GV01050B) ,  Condensed derivatives of pyrane  (CF07093I)

Terms in the title (4)： アロマターゼ ,  阻害活性 ,  クマリン誘導体 ,  評価