Art

J-GLOBAL ID：201802249244122541   Reference number：18A1155060

Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease

パーキンソン病におけるオートファジー増強剤の治療可能性【JST・京大機械翻訳】

Author (8)： Moors Tim E. (Department of Anatomy and Neurosciences, Section Clinical Neuroanatomy, Amsterdam Neuroscience, VU University Medical Center Amsterdam, Amsterdam, The Netherlands) ,  Hoozemans Jeroen J. M. (Department of Pathology, Amsterdam Neuroscience, VU University Medical Center Amsterdam, Amsterdam, The Netherlands) ,  Ingrassia Angela (Department of Anatomy and Neurosciences, Section Clinical Neuroanatomy, Amsterdam Neuroscience, VU University Medical Center Amsterdam, Amsterdam, The Netherlands) ,  Beccari Tommaso (Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy) ,  Parnetti Lucilla (Department of Medicine, Section of Neurology, University of Perugia, Perugia, Italy) ,  Chartier-Harlin Marie-Christine (UMR-S 1172-JPArc-Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer, University of Lille, Lille, France) ,  Chartier-Harlin Marie-Christine (Inserm, UMR-S 1172, Team “Early stages of Parkinson’s disease”, Lille, France) ,  Berg Wilma D. J. van de (Department of Anatomy and Neurosciences, Section Clinical Neuroanatomy, Amsterdam Neuroscience, VU University Medical Center Amsterdam, Amsterdam, The Netherlands)
Material： Molecular Neurodegeneration (Web)
Volume： 12  Issue： 1  Page： 11  Publication year： 2017 
JST Material Number： U7339A  ISSN： 1750-1326  Document type： Article
Article type： 文献レビュー  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Converging evidence from genet...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A1155060&from=J-GLOBAL&jstjournalNo=U7339A") }}

Thesaurus term： cell death ,  characterization ,  chaperone protein ,  pharmacology ,  *Parkinson's disease ,  pathology ,  targeting ,  *autophagy ,  aggregation ,  dysfunction ,  transcription factor ,  oxidative stress ,  lysosome ,  gene ,  proteolysis

JST classification (1)： Cell physiology in general  (EF02010S)

Reference (172)：

• Proc Natl Acad Sci U S A; alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with lewy bodies; MG Spillantini, RA Crowther, R Jakes, M Hasegawa, M Goedert; 95; 1998; 6469-6473; 10.1073/pnas.95.11.6469; CR1;
• Mol Neurobiol; alpha-Synuclein and protein degradation systems: a reciprocal relationship; M Xilouri, OR Brekk, L Stefanis; 47; 2013; 537-551; 10.1007/s12035-012-8341-2; CR2;
• Acta Neuropathol; Protein degradation pathways in Parkinson’s disease: curse or blessing; D Ebrahimi-Fakhari, L Wahlster, PJ Mclean; 124; 2012; 153-172; 10.1007/s00401-012-1004-6; CR3;
• J Biol Chem; Alpha-Synuclein is degraded by both autophagy and the proteasome; JL Webb, B Ravikumar, J Atkins, JN Skepper, DC Rubinsztein; 278; 2003; 25009-25013; 10.1074/jbc.M300227200; CR4;
• Mov Disord; Autophagy and alpha-synuclein: relevance to Parkinson’s disease and related synucleopathies; M Xilouri, OR Brekk, L Stefanis; 31; 2016; 178-192; 10.1002/mds.26477; CR5;

Terms in the title (5)： パーキンソン病 ,  オートファジー ,  増強 ,  治療 ,  可能性