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J-GLOBAL ID：201802250402838047   Reference number：18A1910022

R-THP-COP versus R-CHOP in patients younger than 70 years with untreated diffuse large B cell lymphoma: A randomized, open-label, noninferiority phase 3 trial

未治療びまん性大細胞型B細胞リンパ腫を有する70歳未満の患者におけるR-THP-COP対R-CHOP:無作為化,オープンラベル,非劣性第3相試験【JST・京大機械翻訳】

Author (26)： Hara Takeshi (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Hara Takeshi (Department of Hematology, Matsunami General Hospital, Kasamatsu, Japan) ,  Yoshikawa Takeshi (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Goto Hideko (Division of Hematology, Gifu Municipal Hospital, Gifu, Japan) ,  Sawada Michio (Department of Hematology, Gifu Red-Cross Hospital, Gifu, Japan) ,  Yamada Toshiki (Department of Hematology, Gifu Prefectural General Medical Center, Gifu, Japan) ,  Fukuno Kenji (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Kasahara Senji (Division of Hematology, Gifu Municipal Hospital, Gifu, Japan) ,  Shibata Yuhei (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Matsumoto Takuro (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Mabuchi Ryoko (Department of Internal Medicine, Kisogawa Municipal Hospital, Kisogawa, Japan) ,  Nakamura Nobuhiko (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Nakamura Hiroshi (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Ninomiya Soranobu (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Kitagawa Junichi (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Kanemura Nobuhiro (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Nannya Yasuhito (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Katsumura Naoki (Department of Internal Medicine, Chuno Kosei Hospital, Seki, Japan) ,  Takahashi Takeshi (Department of Hematology, Matsunami General Hospital, Kasamatsu, Japan) ,  Kito Yusuke (Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Takami Tsuyoshi (Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Miyazaki Tatsuhiko (Pathology Division, Gifu University Hospital, Gifu, Japan) ,  Takeuchi Tamotsu (Department of Pathology and Translational Research, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Shimizu Masahito (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Tsurumi Hisashi (First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan) ,  Tsurumi Hisashi (Department of Hematology, Matsunami General Hospital, Kasamatsu, Japan)
Material： Hematological Oncology  (Haematol Oncol)
Volume： 36  Issue： 4  Page： 638-644  Publication year： 2018 
JST Material Number： D0357E  ISSN： 0278-0232  CODEN： HAONDL  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Pirarubicin (tetrahydropyranyl...

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Thesaurus term： safety ,  survival ratio ,  confidence interval ,  acute myeloid leukemia ,  *patient ,  *phase 3 study ,  median value ,  *recessive ,  *therapy ,  amino sugar ,  quinone ,  nitrogen heterocyclic compound ,  oxygen heterocyclic compound ,  polyphenol ,  deoxysugar ,  pyranoside ,  polynuclear aromatic compound
Semi thesaurus term： 5年全生存率 ,  完全寛解 ,  レジメン ,  *R-CHOP療法 ,  リツキシマブ , 【Automatic Indexing@JST】

Author keywords (5)： diffuse large B cell lymphoma (DLBCL) ,  non-Hodgkin’s lymphoma (NHL) ,  pirarubicin (THP) ,  R-CHOP ,  R-THP-COP

JST classification (2)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C) ,  Blood cell tumors(=neoplasms)  (GK04000M)

Substance index (1)： Anthracycline

Terms in the title (8)： 治療 ,  びまん性大細胞型B細胞リンパ腫 ,  患者 ,  COP ,  R-CHOP ,  ラベル ,  劣性 ,  第3相試験