Art

J-GLOBAL ID：201802250954789735   Reference number：18A1361300

Synthesis of 1,5-Anhydro-d-fructose derivatives and evaluation of their inflammasome inhibitors

1,5-アンヒドロ-D-フルクトース誘導体の合成とそれらのインフラマソーム阻害剤の評価【JST・京大機械翻訳】

Author (10)： Goto Kohtaro (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan) ,  Ideo Hiroko (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan) ,  Tsuchida Akiko (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan) ,  Hirose Yuriko (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan) ,  Maruyama Ikuro (Department of Systems Biology in Thromboregulation, Kagoshima University, Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima-City, Kagoshima 890-8520, Japan) ,  Noma Satoshi (Department of Systems Biology in Thromboregulation, Kagoshima University, Graduate School of Medical and Dental Sciences, 8-35-1, Sakuragaoka, Kagoshima-City, Kagoshima 890-8520, Japan) ,  Shirai Takashi (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan) ,  Amano Junko (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan) ,  Mizuno Mamoru (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan) ,  Matsuda Akio (The Noguchi Institute, 1-9-7, Kaga, Itabashi-Ku, Tokyo 173-0003, Japan)
Material： Bioorganic & Medicinal Chemistry  (Bioorganic and Medicinal Chemistry)
Volume： 26  Issue： 13  Page： 3763-3772  Publication year： 2018 
JST Material Number： W0556A  ISSN： 0968-0896  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Synthesis of several 1,5-Anhyd...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A1361300&from=J-GLOBAL&jstjournalNo=W0556A") }}

Thesaurus term： steric conformation ,  *hydration ,  human ,  dimer ,  *Inflammasomes ,  inhibitory activity ,  bone marrow macrophage ,  nod-like receptor protein 3
Semi thesaurus term： *阻害剤 , 【Automatic Indexing@JST】

Author keywords (5)： Carbohydrates ,  1 5-Anhydro-d-fructose derivatives ,  Enones ,  Inflammasome ,  NLRP3

JST classification (2)： Synthesis of drugs  (GV01030F) ,  Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W)

Substance index (1)： 1,5-Anhydro-D-fructose

Terms in the title (5)： D-フルクトース ,  誘導体 ,  インフラマソーム ,  阻害剤 ,  評価