Art

J-GLOBAL ID：201802251539368895   Reference number：18A1197067

Exogenous gene transfer of Rab 3 8 small GTPase ameliorates aberrant lung surfactant homeostasis in Ruby rats

Rab38小GTPアーゼの外因性遺伝子導入はルビーラットにおける異常な肺サーファクタント恒常性を改善する【JST・京大機械翻訳】

Author (10)： Osanai Kazuhiro (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Nakase Keisuke (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Sakuma Takashi (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Nishiki Kazuaki (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Nojiri Masafumi (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Kato Ryo (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Saito Masatoshi (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Fujimoto Yuki (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Mizuno Shiro (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan) ,  Toga Hirohisa (Department of Respiratory Medicine, Kanazawa Medical University, Ishikawa, Japan)
Material： Respiratory Research (Web)
Volume： 18  Issue： 1  Page： 70  Publication year： 2017 
JST Material Number： U7545A  ISSN： 1465-993X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Background Rab³8 sm...

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Thesaurus term： phenotype ,  bronchus ,  human(primates) ,  *gene introduction ,  lecithin ,  intracellular transport ,  *rat ,  pulmonary alveolus ,  infection ,  *gene ,  hemorrhagic diathesis ,  wild type ,  secretion(physiology) ,  mutation ,  *pulmonary surfactant

Author keywords (6)： Rab38 GTPase ,  Ruby rats ,  Gene transfer ,  Adenovector ,  Lung surfactant ,  Hermansky-Pudlak syndrome

JST classification (3)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U) ,  Lung  (EJ05020K)

Reference (37)：

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• Am J Pathol; A mutation in Rab38 small GTPase causes abnormal lung surfactant homeostasis and aberrant alveolar structure in mice; K Osanai, R Oikawa, J Higuchi, M Kobayashi, K Tsuchihara, M Iguchi, H Jongsu, H Toga, DR Voelker; 173; 2008; 1265-74; 10.2353/ajpath.2008.080056; CR4;
• Traffic; The cell biology of Hermansky-Pudlak syndrome: recent advances; SM Pietro, EC Dell'Angelica; 6; 2005; 525-33; 10.1111/j.1600-0854.2005.00299.x; CR5;

Terms in the title (6)： GTPアーゼ ,  遺伝子導入 ,  ルビー ,  ラット ,  肺サーファクタント ,  恒常性