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J-GLOBAL ID：201802253156092129   Reference number：18A0933799

Continuous application of compressive force induces fusion of osteoclast-like RAW264.7 cells via upregulation of RANK and downregulation of LGR4

圧縮力の連続的応用はLGR4のランクとダウンレギュレーションを介して破骨細胞様RAW264.7細胞の融合を誘導する【JST・京大機械翻訳】

Author (21)： Matsuike Rieko (Nihon University Graduate School of Dentistry, Tokyo, Japan) ,  Tanaka Hideki (Department of Oral Health Sciences, Nihon University School of Dentistry, Tokyo, Japan) ,  Tanaka Hideki (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan) ,  Nakai Kumiko (Department of Oral Health Sciences, Nihon University School of Dentistry, Tokyo, Japan) ,  Nakai Kumiko (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan) ,  Kanda Mai (Nihon University Graduate School of Dentistry, Tokyo, Japan) ,  Nagasaki Maki (Nihon University Graduate School of Dentistry, Tokyo, Japan) ,  Murakami Fumiko (Nihon University Graduate School of Dentistry, Tokyo, Japan) ,  Shibata Chika (Nihon University Graduate School of Dentistry, Tokyo, Japan) ,  Mayahara Kotoe (Department of Orthodontics, Nihon University School of Dentistry, Tokyo, Japan) ,  Mayahara Kotoe (Division of Clinical Research, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan) ,  Nakajima Akira (Department of Orthodontics, Nihon University School of Dentistry, Tokyo, Japan) ,  Nakajima Akira (Division of Clinical Research, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan) ,  Tanabe Natsuko (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan) ,  Tanabe Natsuko (Department of Biochemistry, Nihon University School of Dentistry, Tokyo, Japan) ,  Kawato Takayuki (Department of Oral Health Sciences, Nihon University School of Dentistry, Tokyo, Japan) ,  Kawato Takayuki (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan) ,  Maeno Masao (Department of Oral Health Sciences, Nihon University School of Dentistry, Tokyo, Japan) ,  Maeno Masao (Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan) ,  Shimizu Noriyoshi (Department of Orthodontics, Nihon University School of Dentistry, Tokyo, Japan) ,  Shimizu Noriyoshi (Division of Clinical Research, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 201  Page： 30-36  Publication year： 2018 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： During orthodontic treatment, ...

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Thesaurus term： mRNA ,  differentiation(biology) ,  *RAW264.7 cell ,  RANKL ,  transmembrane protein ,  receptor ,  *down-regulation ,  NF-kappaB ,  *osteoclast ,  bone resorption ,  up-regulation
Semi thesaurus term： NFATc1 ,  NF-AT ,  TRAP ,  NF-κB活性化受容体 , 【Automatic Indexing@JST】

Author keywords (6)： Osteoclast ,  Cell Fusion ,  Compressive force ,  RANK ,  LGR4 ,  RAW264.7 cells

JST classification (4)： Basic research of anti-inflammatory drugs  (GW15010T) ,  Basic dentistry(= odontology)  (GT01020O) ,  Cell physiology in general  (EF02010S) ,  Basic research of pharmacology of crude drugs  (GX06020J)

Terms in the title (7)： 圧縮力 ,  応用 ,  ダウンレギュレーション ,  破骨細胞 ,  細胞 ,  融合 ,  誘導