Art

J-GLOBAL ID：201802253371595278   Reference number：18A0118641

Superior Microvascular Perfusion of Infused Liposome-Encapsulated Hemoglobin Prior to Reductions in Infarctions after Transient Focal Cerebral Ischemia

一時的な局所脳虚血後の梗塞の減少の前での注入リポソームカプセル封入ヘモグロビンの優れた微小血管潅流

Author (10)： Shimbo Daisuke (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Abumiya Takeo (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Kurisu Kota (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Osanai Toshiya (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Shichinohe Hideo (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Nakayama Naoki (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Kazumata Ken (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Nakamura Hideki (Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Shimuzu Hiroshi (Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan) ,  Houkin Kiyohiro (Department of Neurosurgery, Hokkaido University Graduate School of Medicine, Sapporo, Japan)
Material： Journal of Stroke & Cerebrovascular Diseases  (J Stroke Cerebrovasc Dis)
Volume： 26  Issue： 12  Page： 2994-3003  Publication year： Dec. 2017 
JST Material Number： W1420A  ISSN： 1052-3057  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： transient cerebral ischemia ,...
Semi thesaurus term： *リポソームカプセル封入ヘモグロビン ,...

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Author keywords (4)： Infarction ,  transient focal cerebral ischemia ,  microvessels ,  neuroprotection

JST classification (1)： Basic neurology  (GN01020W)

Reference (26)：

• Molina, C.A., Alvarez-Sabin, J. Recanalization and reperfusion therapies for acute ischemic stroke. Cerebrovasc Dis. 2009;27:162-167.
• Hauck, E.F., Apostel, S., Hoffmann, J.F. et al, Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy. J Cereb Blood Flow Metab. 2004;24:383-391.
• Ito, U., Hakamata, Y., Kawakami, E. et al, Temporary focal cerebral ischemia results in swollen astrocytic end-feet that compress microvessels and lead to delayed focal cortical infarction. J Cereb Blood Flow Metab. 2011;31:328-338.
• Kurisu, K., Abumiya, T., Nakamura, H. et al, Transarterial regional brain hypothermia inhibits acute aquaporin-4 surge and sequential microvascular events in ischemia/reperfusion injury. Neurosurgery. 2016;79:125-134.
• Kaneda, S., Ishizuka, T., Goto, H. et al, Liposome-encapsulated hemoglobin, trm-645: current status of the development and important issues for clinical application. Artif Organs. 2009;33:146-152.

Terms in the title (8)： 局所脳虚血 ,  梗塞 ,  注入 ,  リポソーム ,  カプセル封入 ,  ヘモグロビン ,  微小血管 ,  潅流