Art

J-GLOBAL ID：201802253844653943   Reference number：18A0364715

Generation of allo-antigen-specific induced Treg stabilized by vitamin C treatment and its application for prevention of acute graft versus host disease model

ビタミンCにより安定化されたアロ抗原特異的誘導性Tregの生成及び急性移植片対宿主病モデルの予防のためのその応用

Author (11)： KASAHARA Hidenori (Keio Univ. School of Medicine, Tokyo, JPN) ,  KONDO Taisuke (Keio Univ. School of Medicine, Tokyo, JPN) ,  NAKATSUKASA Hiroko (Keio Univ. School of Medicine, Tokyo, JPN) ,  CHIKUMA Shunsuke (Keio Univ. School of Medicine, Tokyo, JPN) ,  ITO Minako (Keio Univ. School of Medicine, Tokyo, JPN) ,  ANDO Makoto (Keio Univ. School of Medicine, Tokyo, JPN) ,  KUREBAYASHI Yutaka (Keio Univ. School of Medicine, Tokyo, JPN) ,  SEKIYA Takashi (National Center for Global Health and Medicine, Chiba, JPN) ,  YAMADA Taketo (Saitama Medical Univ., Saitama, JPN) ,  OKAMOTO Shinichiro (Keio Univ. School of Medicine, Tokyo, JPN) ,  YOSHIMURA Akihiko (Keio Univ. School of Medicine, Tokyo, JPN)
Material： International Immunology  (Int Immunol)
Volume： 29  Issue： 10  Page： 457-469  Publication year： Oct. 2017 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： experimental disease ,...
Semi thesaurus term： DNA demethylation ,...

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JST classification (2)： Transplantation immunity  (ED03020E) ,  Vitamin C  (EB07040W)

Substance index (1)： Ascorbic Acid

Reference (47)：

• Holtan, S. G.,Pasquini, M. and Weisdorf, D. J. 2014. Acute graft-versus-host disease: a bench-to-bedside update. Blood 124:363.
• Koyama, M., Kuns, R. D., Olver, S. D.et al. 2011. Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease. Nat. Med . 18:135.
• Blazar, B. R.,Murphy, W. J. and Abedi, M. 2012. Advances in graft-versus-host disease biology and therapy. Nat. Rev. Immunol . 12:443.
• Markey, K. A.,MacDonald, K. P. and Hill, G. R. 2014. The biology of graft-versus-host disease: experimental systems instructing clinical practice. Blood 124:354.
• Kanamori, M.,Nakatsukasa, H.,Okada, M.,Lu, Q. and Yoshimura, A. 2016. Induced regulatory T cells: their development, stability, and applications. Trends Immunol . 37:803.

Terms in the title (8)： ビタミンC ,  安定化 ,  アロ抗原 ,  誘導性Treg ,  急性移植片対宿主病 ,  モデル ,  予防 ,  応用