Art

J-GLOBAL ID：201802253903248055   Reference number：18A0000693

Clonal deletion of T cell repertoires with specific T cell receptor Vβ chains by two endogenous superantigens in NC/Nga mice

NC/Ngaマウスにおける2つの内因性スーパー抗原による,特定のT細胞受容体Vβ鎖を有するT細胞レパートリーのクローン欠失

Author (3)： OHKUSU-TSUKADA Kozo (Nippon Veterinary & Life-science Univ., Tokyo, JPN) ,  TSUKADA Teruyo (RIKEN, Saitama, JPN) ,  TAKAHASHI Kimimasa (Nippon Veterinary & Life-science Univ., Tokyo, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 81  Issue： 11  Page： 2160-2163  Publication year： Nov. 2017 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 短報  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： mouse(animal) ,...
Semi thesaurus term： Minor Lymphocyte Stimulatory Loci ,...

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JST classification (4)： Immunological reaction in general  (ED03010T) ,  Gene expression  (EC02040Q) ,  Basic dermatology  (GF01020Y) ,  Immunologic diseases,allergic diseases in general.  (GD04010C)

Reference (15)：

• Acha-Orbea H, Held W, Waanders GA, et al. Exogenous and endogenous mouse mammary tumor virus superantigens. Immunol Rev. 1993;131:5-25.
• Waanders GA, McDonald HR. Hierarchy of responsiveness in vivo and in vitro among T cells expressing distinct Mls-1^a-reactive V beta domains. Eur J Immunol. 1992;22:291-293.
• Conrad B, Weissmahr RN, Böni J, et al. A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes. Cell. 1997;90:303-313.
• Sutkowski N, Conrad B, Thorley-Lawson DA, et al. Epstein-barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen. Immunity. 2001;15:579-589.
• Nelson P, Rylance P, Roden D, et al. Viruses as potential pathogenic agents in systemic lupus erythematosus. Lupus. 2014;23:596-605.

Terms in the title (8)： NC ,  マウス ,  内因性 ,  スーパー抗原 ,  T細胞受容体 ,  T細胞 ,  クローン ,  欠失