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J-GLOBAL ID：201802254171140341   Reference number：18A1850519

Synthesis of 2,2-Dialkyl Chromanes by Intramolecular Ullmann C-O Coupling Reactions toward the Total Synthesis of D-α-Tocopherol

D-α-トコフェロールの全合成に向けた分子内Ullmann C-Oカップリング反応による2,2-ジアルキルクロマン類の合成

Author (6)： Tsubogo Tetsu (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Tsubogo Tetsu (Division of Fusion of Regenerative Medicine with DDS, Research Institute for Science and Technology (RIST), Tokyo University of Science) ,  Aoyama Saki (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Takeda Rika (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Uchiro Hiromi (Faculty of Pharmaceutical Sciences, Tokyo University of Science) ,  Uchiro Hiromi (Division of Fusion of Regenerative Medicine with DDS, Research Institute for Science and Technology (RIST), Tokyo University of Science)
Material： Chemical and Pharmaceutical Bulletin (Web)
Volume： 66  Issue： 9  Page： 843-846(J-STAGE)  Publication year： 2018 
JST Material Number： U1401A  ISSN： 1347-5223  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *total synthesis ,...

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Author keywords (6)： Ullmann C-O coupling reaction ,  D-α-tocopherol ,  22-dialkyl chromane ,  Ullmann C-O coupling reaction ,  D-α-tocopherol ,  22-dialkyl chromane

JST classification (3)： Addition reaction,elimination reaction  (CF02030M) ,  Oxygen heterocycles in general  (CF07020K) ,  Vitamin E  (EB07060S)

Substance index (2)： Chromanol C1 ,  TPGS

Reference (47)：

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• 4) Traber M. G., Atkinson J., Free Radic. Biol. Med., 43, 4-15 (2007).
• 5) Meydani S. N., Han S. N., Wu D., Immunol. Rev., 205, 269-284 (2005).

Terms in the title (3)： d-α-トコフェロール ,  全合成 ,  カップリング反応