Art

J-GLOBAL ID：201802255365489787   Reference number：18A0129629

Intranasal administration of neuromedin U derivatives containing cell-penetrating peptides and a penetration-accelerating sequence induced memory improvements in mice

細胞透過性ペプチドを含むニューロメジンU誘導体の鼻腔内投与とマウスにおける貫通促進配列誘導される記憶の改善【Powered by NICT】

Author (14)： Sasaki-Hamada Sachie (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Sasaki-Hamada Sachie (Center for Translational Research, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Funane Taichi (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Nakao Yusuke (Laboratory of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Sasaki Rie (Laboratory of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Nagai Mio (Laboratory of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Ueta Yudai (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Yoshizawa Kazumi (Laboratory of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Horiguchi Michiko (Laboratory of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Horiguchi Michiko (Center for Drug Delivery Research, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Yamashita Chikamasa (Laboratory of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Yamashita Chikamasa (Center for Drug Delivery Research, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Oka Jun-Ichiro (Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan) ,  Oka Jun-Ichiro (Center for Translational Research, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan)
Material： Peptides (N.Y.)
Volume： 99  Page： 241-246  Publication year： 2018 
JST Material Number： W0486A  ISSN： 0196-9781  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Neuromedin U (NMU) is a neurop...

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Thesaurus term： paraventricular nucleus ,  memory disorder ,  hippocampus ,  *administration(biology) ,  *intranasal administration ,  therapy ,  inflammation ,  neuropeptide ,  lipopolysaccharide ,  cerebral ventricles ,  amnesia
Semi thesaurus term： *ニューロメジンU ,  *細胞貫通性ペプチド , 【Automatic Indexing@JST】

Author keywords (4)： Neuromedin U ,  Learning and memory ,  Intranasal administration ,  Brain drug delivery and targeting

JST classification (1)： Bioactive peptides  (EB08100U)

Terms in the title (7)： 細胞透過性ペプチド ,  ニューロメジンU ,  誘導体 ,  鼻腔内投与 ,  マウス ,  促進 ,  誘導