Art

J-GLOBAL ID：201802255891393625   Reference number：18A1330612

High levels of serum Mac-2-binding protein glycosylation isomer (M2BPGi) predict the development of hepatocellular carcinoma in hepatitis B patients treated with nucleot(s)ide analogues

高レベルの血清Mac-2結合蛋白糖鎖修飾異性体(M2BPGi)はヌクレオチド/ヌクレオシド類似体で治療したB型肝炎患者において肝細胞癌の発症を予測する

Author (10)： SHINKAI Noboru (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  NOJIMA Masanori (Univ. Tokyo, Tokyo, JPN) ,  IIO Etsuko (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  MATSUNAMI Kayoko (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  TOYODA Hidenori (Ogaki Municipal Hospital, Ogaki, JPN) ,  MURAKAMI Shuko (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  INOUE Takako (Nagoya City Univ. Hospital, Nagoya, JPN) ,  OGAWA Shintaro (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  KUMADA Takashi (Ogaki Municipal Hospital, Ogaki, JPN) ,  TANAKA Yasuhito (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN)
Material： Journal of Gastroenterology  (J Gastroenterol)
Volume： 53  Issue： 7  Page： 883-889  Publication year： 2018 
JST Material Number： Z0748A  ISSN： 0944-1174  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *membrane glycoprotein ,...
Semi thesaurus term： serodiagnosis ,...

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JST classification (3)： Proteins and peptides in general  (EB03010N) ,  Tumors(=neoplasms)of digestive system  (GH04000D) ,  Clinical oncology in general  (GE03010Y)

Substance index (2)： Entecavir ,  Tenofovir disoproxil fumarate

Reference (24)：

• Lai CL, Ratziu V, Yuen MF, et al. Viral hepatitis B. Lancet (London, England). 2003;362(9401):2089-94.
• Chen CJ, Yu MW, Liaw YF. Epidemiological characteristics and risk factors of hepatocellular carcinoma. J Gastroenterol Hepatol. 1997;12(9-10):S294-308.
• Liaw YF, Sung JJ, Chow WC, et al. Lamivudine for patients with chronic hepatitis B and advanced liver disease. N Engl J Med. 2004;351(15):1521-31.
• Chang TT, Liaw YF, Wu SS, et al. Long-term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B. Hepatology (Baltimore, MD). 2010;52(3):886-93.
• Marcellin P, Gane E, Buti M, et al. Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study. Lancet (London, England). 2013;381(9865):468-75.

Terms in the title (12)： 高レベル ,  血清 ,  Mac-2結合蛋白糖鎖修飾異性体 ,  M2BPGi ,  ヌクレオチド ,  ヌクレオシド類似体 ,  治療 ,  B型肝炎 ,  患者 ,  肝細胞癌 ,  発症 ,  予測