Art

J-GLOBAL ID：201802257296348773   Reference number：18A1014025

Acidic conditions induce the suppression of CD86 and CD54 expression in THP-1 cells

酸性条件はTHP-1細胞におけるCD86およびCD54発現抑制を誘導する

Author (4)： Mitachi Takafumi (Department of Chemical and Energy Engineering, Yokohama National University) ,  Mezaki Minori (Department of Chemical and Energy Engineering, Yokohama National University) ,  Yamashita Kunihiko (Corporate Research Center, Daicel Corporation) ,  Itagaki Hiroshi (Department of Chemical and Energy Engineering, Yokohama National University)
Material： Journal of Toxicological Sciences  (J Toxicol Sci)
Volume： 43  Issue： 5  Page： 299-309(J-STAGE)  Publication year： 2018 
JST Material Number： Z0265B  ISSN： 0388-1350  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： ion pump(organism) ,...
Semi thesaurus term： *CD54 ,...

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Author keywords (5)： Sensitization ,  pH ,  CD86 ,  CD54 ,  Allergen

JST classification (2)： Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Basic dermatology  (GF01020Y)

Substance index (2)： 1-Chloro-2,4-dinitrobenzene ,  Imidazolidinyl urea

Reference (40)：

• Ade, N., Antonios, D., Kerdine-Romer, S., Boisleve, F., Rousset, F. and Pallardy, M. (2007): NF-κB plays a major role in the maturation of human dendritic cells induced by NiSO(4) but not by DNCB. Toxicol. Sci., 99, 488-501.
• Aiba, S., Terunuma, A., Manome, H. and Tagami, H. (1997): Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules. Eur. J. Immunol., 27, 3031-3038.
• Aiba, S., Manome, H., Nakagawa, S., Mollah, Z.U., Mizuashi, M., Ohtani, T., Yoshino, Y. and Tagami, H. (2003): p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl₂ and 2,4-dinitrochlorobenzene. J. Invest. Dermatol., 120, 390-399.
• Arrighi, J.F., Rebsamen, M., Rousset, F., Kindler, V. and Hauser, C. (2001): A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers. J. Immunol., 166, 3837-3845.
• Ashikaga, T., Sakaguchi, H., Sono, S., Kosaka, N., Ishikawa, M., Nukada, Y., Miyazawa, M., Ito, Y., Nishiyama, N. and Itagaki, H. (2010): A comparative evaluation of in vitro skin sensitisation tests: the human cell-line activation test (h-CLAT) versus the local lymph node assay (LLNA). Altern. Lab. Anim., 38, 275-284.

Terms in the title (6)： 酸性条件 ,  THP-1細胞 ,  CD86 ,  CD54 ,  発現抑制 ,  誘導