Art
J-GLOBAL ID：201802257382052231   Reference number：18A1646284

X-ray irradiation induces disruption of the blood-brain barrier with localized changes in claudin-5 and activation of microglia in the mouse brain

X線照射はマウス脳におけるクローディン-5の局在変化およびミクログリアの活性化により血液脳関門の破壊を誘導する【JST・京大機械翻訳】
Author (6)：
Yoshida Yukari

About Yoshida Yukari

(Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan)

About Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan

, 
Sejimo Yukihiko

About Sejimo Yukihiko

(Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan)

About Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan

, 
Kurachi Masashi

About Kurachi Masashi

(Department of Molecular and Cellular Neurobiology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan)

About Department of Molecular and Cellular Neurobiology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan

, 
Ishizaki Yasuki

About Ishizaki Yasuki

(Department of Molecular and Cellular Neurobiology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan)

About Department of Molecular and Cellular Neurobiology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan

, 
Nakano Takashi

About Nakano Takashi

(Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan)

About Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan

, 
Takahashi Akihisa

About Takahashi Akihisa

(Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan)

About Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan


Material：
Neurochemistry International  (Neurochem Int)

About Neurochemistry International


Volume： 119  Page： 199-206  Publication year： 2018 
JST Material Number： E0890A  ISSN： 0197-0186  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
X-ray irradiation (X-irradiati...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
time dependence

About time dependence

, 
Proteins

About Proteins

, 
*microglia

About microglia

, 
*Blood-Brain Barrier

About Blood-Brain Barrier

, 
*X-ray irradiation

About X-ray irradiation

, 
Down-Regulation

About Down-Regulation

, 
single administration

About single administration

, 
vascular endothelial cell

About vascular endothelial cell

, 
*X-ray

About X-ray

, 
cerebral cortex

About cerebral cortex

, 
Claudins

About Claudins

, 
*Claudin-5

About Claudin-5

, 
immune response

About immune response

, 
*Cardiovascular System

About Cardiovascular System

, 
cortex

About cortex

, 
telencephalon

About telencephalon


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
immunological reaction

About immunological reaction

, 
VEGF

About VEGF

, 
透過性

About 透過性

, 【Automatic Indexing@JST】
Author keywords (6)：
X-ray

About X-ray

, 
Blood-brain barrier

About Blood-brain barrier

, 
TNF-α

About TNF-α

, 
NF-κB

About NF-κB

, 
Microglia

About Microglia

, 
Claudin-5

About Claudin-5

JST classification (5)：
JST classification
Category name(code) classified by JST.
Central nervous system 
(EJ12030F)

About Central nervous system

,  Biological function 
(EB03040U)

About Biological function

,  Cell physiology in general 
(EF02010S)

About Cell physiology in general

,  Basic neurology 
(GN01020W)

About Basic neurology

,  Cytokines 
(EB08090G)

About Cytokines

Terms in the title (9)：
Terms in the title
Keywords automatically extracted from the title.
X線照射

About X線照射

, 
マウス

About マウス

, 
脳

About 脳

, 
クローディン-5

About クローディン-5

, 
ミクログリア

About ミクログリア

, 
活性化

About 活性化

, 
血液脳関門

About 血液脳関門

, 
破壊

About 破壊

, 
誘導

About 誘導


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