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J-GLOBAL ID：201802257510647195   Reference number：18A0287933

The Highly Dynamic Nature of ERdj5 Is Key to Efficient Elimination of Aberrant Protein Oligomers through ER-Associated Degradation

ERdj5の高度に動的な性質は小胞体関連分解による異常蛋白質オリゴマーの効率的な除去に重要である【Powered by NICT】

Author (18)： Maegawa Ken-ichi (Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai 980-8577, Japan) ,  Maegawa Ken-ichi (CREST, JST, Japan) ,  Watanabe Satoshi (Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai 980-8577, Japan) ,  Watanabe Satoshi (CREST, JST, Japan) ,  Noi Kentaro (Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Noi Kentaro (CREST, JST, Japan) ,  Okumura Masaki (Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai 980-8577, Japan) ,  Amagai Yuta (Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai 980-8577, Japan) ,  Inoue Michio (Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai 980-8577, Japan) ,  Inoue Michio (CREST, JST, Japan) ,  Ushioda Ryo (Department of Molecular Biosciences, Kyoto Sangyo University, Kyoto 603-8455, Japan) ,  Ushioda Ryo (CREST, JST, Japan) ,  Nagata Kazuhiro (Department of Molecular Biosciences, Kyoto Sangyo University, Kyoto 603-8455, Japan) ,  Nagata Kazuhiro (CREST, JST, Japan) ,  Ogura Teru (Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan) ,  Ogura Teru (CREST, JST, Japan) ,  Inaba Kenji (Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai 980-8577, Japan) ,  Inaba Kenji (CREST, JST, Japan)
Material： Structure
Volume： 25  Issue： 6  Page： 846-857.e4  Publication year： 2017 
JST Material Number： A1212A  ISSN： 0969-2126  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： ERdj5, composed of an N-termin...

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Thesaurus term： visualization ,  cluster ,  protein disulfide-isomerase ,  crystal structure ,  *endoplasmic reticulum ,  *oligomer ,  steric conformation ,  substrate(biochemistry) ,  disulfide bond ,  thioredoxin
Semi thesaurus term： X線結晶構造解析 ,  C末端 ,  ドメイン構造 ,  *小胞体関連分解 ,  *ERdj5 , 【Automatic Indexing@JST】

Author keywords (5)： ERAD ,  ERdj5 ,  high-speed AFM ,  X-ray crystal structure analysis ,  single-molecule analysis

JST classification (2)： Cell physiology in general  (EF02010S) ,  Function of cell components  (EF03060C)

Terms in the title (5)： ERdj5 ,  性質 ,  小胞体関連分解 ,  異常蛋白質 ,  オリゴマー