Art

J-GLOBAL ID：201802258135585097   Reference number：18A0529176

Protein neddylation and its alterations in human cancers for targeted therapy

標的治療のためのヒト癌における蛋白質NEDD化とその変化【Powered by NICT】

Author (5)： Zhou Lisha (Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China) ,  Zhang Wenjuan (Cancer Institute, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China) ,  Sun Yi (Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang 30029, China) ,  Sun Yi (Division of Radiation and Cancer Biology, Department of Radiation Oncology, University of Michigan, 1301 Catherine Street, Ann Arbor, MI 48109, USA) ,  Jia Lijun (Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China)
Material： Cellular Signalling  (Cell Signal)
Volume： 44  Page： 92-102  Publication year： 2018 
JST Material Number： T0667A  ISSN： 0898-6568  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Neddylation, a post-translatio...

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Thesaurus term： Apoptosis ,  *human ,  *molecular target therapy ,  post-translational modification ,  Ubiquitination ,  antitumor action ,  substrate (biochemistry) ,  *Proteins ,  Autophagy ,  tumorigenesis ,  targeting ,  ligase ,  cell cycle arrest ,  NEDD8
Semi thesaurus term： 癌治療 , 【Automatic Indexing@JST】

Author keywords (8)： Neddylation ,  Cancer target ,  Cullin RING ligase ,  MLN4924 ,  Cell cycle arrest ,  Apoptosis ,  Senescence ,  Autophagy

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (4)： 標的治療 ,  ヒト ,  癌 ,  蛋白質