Art

J-GLOBAL ID：201802258997592823   Reference number：18A0084222

Development of PEGylated aspartic acid-modified liposome as a bone-targeting carrier for the delivery of paclitaxel and treatment of bone metastasis

骨転移のパクリタキセルと治療のデリバリーのための骨標的キャリアとしてのPEG化アスパラギン酸修飾リポソームの開発【Powered by NICT】

Author (9)： Yamashita Shugo (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Katsumi Hidemasa (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Hibino Nozomi (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Isobe Yugo (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Yagi Yumiko (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Tanaka Yuka (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Yamada Saki (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Naito Chihiro (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan) ,  Yamamoto Akira (Department of Biopharmaceutics, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan)
Material： Biomaterials
Volume： 154  Page： 74-85  Publication year： 2018 
JST Material Number： C0964B  ISSN： 0142-9612  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： To prevent bone metastasis, we...

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Thesaurus term： image processing ,  affinity ,  hydroxyapatite ,  drug delivery system ,  intravenous administration ,  *liposome ,  conjugation ,  targeting ,  amino acid ,  aliphatic amine ,  aliphatic carboxylic acid ,  primary amine ,  alicyclic compound ,  fatty acid ,  aromatic carboxylic acid ,  oxygen heterocyclic compound ,  olefin compound ,  bridged compound ,  carboxylate(ester) ,  aminoalcohol ,  aminocarboxylic acid ,  secondary alcohol ,  hydroxy acid ,  hydroxy ketone ,  polyol
Semi thesaurus term： 転移性骨腫瘍 ,  マウスモデル ,  近赤外蛍光 ,  *PEG化 ,  *骨転移 , 【Automatic Indexing@JST】

Author keywords (5)： Drug delivery ,  Liposome ,  Aspartic acid ,  Bone targeting ,  Bone metastasis

JST classification (3)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Basic biopharmacy  (GY01021U) ,  Medical materials  (GA05040H)

Substance index (2)： Aspartic Acid ,  Paclitaxel

Terms in the title (12)： 骨転移 ,  パクリタキセル ,  治療 ,  デリバリー ,  骨 ,  標的 ,  キャリア ,  PEG化 ,  アスパラギン酸 ,  修飾 ,  リポソーム ,  開発