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J-GLOBAL ID：201802259096995076   Reference number：18A0331548

Induction of cell death in pancreatic ductal adenocarcinoma by indirubin 3′-oxime and 5-methoxyindirubin 3′-oxime in vitro and in vivo

in vitroおよびin vivoにおけるインジルビン3′-オキシムと5 メトキシインジルビン 3′ オキシムによる膵管腺癌における細胞死の誘導【Powered by NICT】

Author (12)： Sano Makoto (Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan) ,  Ichimaru Yoshimi (School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Kurita Masahiro (School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Hayashi Emiko (Division of Oncologic Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan) ,  Homma Taku (Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan) ,  Saito Hiroaki (School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Masuda Shinobu (Division of Oncologic Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan) ,  Nemoto Norimichi (Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan) ,  Hemmi Akihiro (Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan) ,  Suzuki Takashi (School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Miyairi Shinichi (School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Hao Hiroyuki (Division of Human Pathology, Department of Pathology and Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan)
Material： Cancer Letters  (Cancer Lett)
Volume： 397  Page： 72-82  Publication year： 2017 
JST Material Number： E0606B  ISSN： 0304-3835  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Pancreatic ductal adenocarcino...

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Thesaurus term： *oxime ,  phosphorylation ,  fibroblast ,  Cell Proliferation ,  *Cell Death ,  antitumor drug ,  heterotrans plantation ,  *Adenocarcinoma ,  Apoptosis ,  cytotoxicity ,  Annexin V ,  cell cycle analysis ,  Cyclin B1 ,  Cellular Spheroids
Semi thesaurus term： スフェロイド ,  *膵管腺癌 , 【Automatic Indexing@JST】

Author keywords (4)： Indirubin 3′-oximes ,  Pancreatic ductal adenocarcinoma ,  Epithelial-stromal interaction ,  Microenvironment

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (5)： インジルビン ,  オキシム ,  膵管腺癌 ,  細胞死 ,  誘導