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J-GLOBAL ID：201802259231269326   Reference number：18A0081591

Dystonia-4 (DYT4)-associated TUBB4A mutants exhibit disorganized microtubule networks and inhibit neuronal process growth

ジストニア4(DYT4)関連TUBB4A変異体は無秩序な微小管ネットワークを示し,神経突起成長を阻害する【Powered by NICT】

Author (9)： Watanabe Natsumi (Laboratory of Molecular Neuroscience and Neurology, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Itakaoka Misa (Laboratory of Molecular Neuroscience and Neurology, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Seki Yoich (Laboratory of Molecular Neuroscience and Neurology, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Morimoto Takako (Laboratory of Molecular Neuroscience and Neurology, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Homma Keiichi (Department of Life Science and Informatics, Maebashi Institute of Technology, Maebashi, Gunma 371-0816, Japan) ,  Miyamoto Yuki (Laboratory of Molecular Neuroscience and Neurology, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Miyamoto Yuki (Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan) ,  Yamauchi Junji (Laboratory of Molecular Neuroscience and Neurology, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan) ,  Yamauchi Junji (Department of Pharmacology, National Research Institute for Child Health and Development, Setagaya, Tokyo 157-8535, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 495  Issue： 1  Page： 346-352  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Dystonia-1 (DYT1) is an autoso...

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Thesaurus term： tubulin ,  gene ,  *network ,  pathology ,  interaction ,  wild type ,  chaperone protein ,  *microtubule ,  cytoplasm ,  dominance ,  autosome ,  *dystonia ,  heredity ,  biochemistry
Semi thesaurus term： *神経突起 , 【Automatic Indexing@JST】

Author keywords (4)： Dystonia-4 ,  TUBB4A ,  Microtubule ,  Process growth

JST classification (5)： Genetic variation  (EC01030Y) ,  Cell physiology in general  (EF02010S) ,  Function of cell components  (EF03060C) ,  Anthropology  (EA01070K) ,  Congenital diseases,deformities in general.  (GD03010V)

Terms in the title (6)： ジストニア ,  変異体 ,  微小管 ,  神経突起 ,  成長 ,  阻害