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J-GLOBAL ID：201802260249314857   Reference number：18A2134941

Therapeutic effects of oral clomiphene citrate in 2 dogs with low plasma testosterone levels and poor semen quality

低血漿テストステロンレベルと低精液品質の2匹のイヌにおけるクエン酸クロミフェン経口投与の治療効果

Author (3)： KOBAYASHI Masanori (Laboratory of Reproduction, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan) ,  HORI Tatsuya (Laboratory of Reproduction, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan) ,  KAWAKAMI Eiichi (Laboratory of Reproduction, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan)
Material： Journal of Veterinary Medical Science (Web)
Volume： 80  Issue： 8  Page： 1233-1235(J-STAGE)  Publication year： 2018 
JST Material Number： U1094A  ISSN： 1347-7439  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *plasma(blood) ,...
Semi thesaurus term： *Semen quality ,...

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Author keywords (5)： clomiphene citrate ,  oral administration ,  semen quality ,  spermatogenic dysfunction ,  testosterone

JST classification (3)： Dogs,cats  (FD06010P) ,  Medical pharmaceuticals for animals  (FE01050B) ,  Reproductive(=genital)organs  (EJ15020P)

Substance index (2)： Testosterone ,  Clomiphene citrate

Reference (11)：

• 1. ElSheikh, M. G., Hosny, M. B., Elshenoufy, A., Elghamrawi, H., Fayad, A. and Abdelrahman, S. 2015. Combination of vitamin E and clomiphene citrate in treating patients with idiopathic oligoasthenozoospermia: A prospective, randomized trial. Andrology 3: 864-867.
• 2. Fontenot, G. K., Wiehle, R. D. and Podolski, J. S. 2016. Differential effects of isomers of clomiphene citrate on reproductive tissues in male mice. BJU Int. 117: 344-350.
• 3. Kaminetsky, J., Werner, M., Fontenot, G. and Wiehle, R. D. 2013. Oral enclomiphene citrate stimulates the endogenous production of testosterone and sperm counts in men with low testosterone: comparison with testosterone gel. J. Sex. Med. 10: 1628-1635.
• 4. Kawakami, E., Kobayashi, M., Hori, T. and Kaneda, T. 2016. Therapeutic effects of vitamin E supplementation in 4 dogs with poor semen quality and low superoxide dismutase activity in seminal plasma. J. Vet. Med. Sci. 77: 1711-1714.
• 5. Kawakami, E., Hori, T. and Tsutsui, T. 1998. Changes in plasma LH and testosterone levels and semen quality after a single injection of hCG in two dogs with spermatogenic dysfunction. J. Vet. Med. Sci. 60: 765-767.

Terms in the title (7)： 血漿 ,  テストステロン ,  精液品質 ,  イヌ ,  クエン酸クロミフェン ,  経口投与 ,  治療効果