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J-GLOBAL ID:201802261615439117   Reference number:18A0504818

『心筋細胞フィジオーム理解のための電子教科書“e-Heart”』の生理学教育教材および研究資材としての活用に向けて 第2回 ヒト心室筋細胞(HuVEC)モデルを用いた早期後脱分極(EAD)の再現

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Material:
Volume: 80  Issue:Page: WEB ONLY  Publication year: Feb. 2018 
JST Material Number: U0640A  ISSN: 0031-9341  Document type: Article
Article type: 解説  Country of issue: Japan (JPN)  Language: JAPANESE (JA)
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Cardiovascular system diseases  ,  Circulatory system models  ,  Heart 
Reference (6):
  • Himeno Y, Asakura K, Cha CY, Memida H, Powell T, Amano A, Noma A: A human ventricular myocyte model with a refined representation of excitationcontraction coupling. Biophys J 109: 415-427, 2015
  • Carmeliet E, Saikawa T: Shortening of the action potential and reduction of pacemaker activity by lidocaine, quinidine, and procainamide in sheep cardiac purkinje fibers. An effect on Na or K currents? Circ Res 50: 257-272, 1982
  • Maltsev VA, Sabbah HN, Higgins RS, Silverman N, Lesch M, Undrovinas AI: Novel, ultraslow inactivating sodium current in human ventricular cardiomyocytes. Circulation 98: 2545-2552, 1998
  • Maltsev VA, Undrovinas AI: A multi-modal composition of the late Na+ current in human ventricular cardiomyocytes. Cardiovasc Res 69: 116-127, 2006
  • Asakura K, Cha CY, Yamaoka H, Horikawa Y, Memida H, Powell T, Amano A, Noma A: EAD and DAD mechanisms analyzed by developing a new human ventricular cell model. Prog Biophys Mol Biol 116: 11-24, 2014
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