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J-GLOBAL ID：201802263102922947   Reference number：18A0312614

A Nuclear Factor Involved in Transcriptional Regulation of the AREBP Gene

核因子はAREBP遺伝子の転写調節に関与する

Author (6)： SHIRAI Tomomi (Department of International Food and Agricultural Science, Faculty of International Agriculture and Food Studies, Tokyo University of Agriculture) ,  SHIRAI Tomomi (Department of Food Function and Labeling, National Institute of Health and Nutrition) ,  TANIOKA Yuri (Department of International Food and Agricultural Science, Faculty of International Agriculture and Food Studies, Tokyo University of Agriculture) ,  FURUSHO Tadasu (Department of International Food and Agricultural Science, Faculty of International Agriculture and Food Studies, Tokyo University of Agriculture) ,  YAMAUCHI Jun (Department of International Food and Agricultural Science, Faculty of International Agriculture and Food Studies, Tokyo University of Agriculture) ,  YAMAUCHI Jun (Department of Food Function and Labeling, National Institute of Health and Nutrition)
Material： Journal of Nutritional Science and Vitaminology  (Nutritional Science and Vitaminology)
Volume： 63  Issue： 6  Page： 430-432(J-STAGE)  Publication year： 2017 
JST Material Number： F0733A  ISSN： 0301-4800  CODEN： JNSVA5  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： transcription factor ,...
Semi thesaurus term： 293T cell ,...

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Author keywords (4)： AREBP ,  AMPK ,  AICAR ,  gluconeogenesis

JST classification (2)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Gene expression  (EC02040Q)

Substance index (1)： AICAR

Reference (9)：

• 1) Hardie DG, Ross FA, Hawley SA. 2012. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nature Rev Mol Cell Biol 13: 251-262.
• 2) Inoue E, Yamauchi J. 2006. AMP-activated protein kinase regulates PEPCK gene expression by direct phosphorylation of a novel zinc finger transcription factor. Biochem Biophys Res Commun 351: 793-799.
• 3) Shirai T, Inoue E, Ishimi Y, Yamauchi J. 2011. AICAR response element binding protein (AREBP), a key modulator of hepatic glucose production regulated by AMPK in vivo. Biochem Biophys Res Commun 414: 287-291.
• 4) Inoue E, Yamashita A, Inoue H, Sekiguchi M, Shiratori A, Yamamoto Y, Tadokoro T, Ishimi Y, Yamauchi J. 2010. Identification of glucose transporter 4 knockdown-dependent transcriptional activation element on the retinol binding protein 4 gene promoter and requirement of the 20 S proteasome subunit for transcriptional activity. J Biol Chem 285: 25545-25553.
• 5) Jahroudi N, Ardekani AM, Greenberger JS. 1996. An NF1-like protein function as a repressor of von Willebrand factor promoter. J Biol Chem 271: 21413-21421.

Terms in the title (4)： 核 ,  因子 ,  遺伝子 ,  転写調節