Art

J-GLOBAL ID：201802263233265795   Reference number：18A0006576

Three-Component, Diastereoselective Prins-Ritter Reaction for cis-Fused 4-Amidotetrahydropyrans toward a Precursor for Possible Neuronal Receptor Ligands

三成分ジアステレオ選択的Prins-Ritter反応によるcis縮合4-アミドテトラヒドロピランを前駆体とする神経受容体配位子の可能性

Author (4)： CHIBA Manami (Yokohama City Univ., Yokohama, JPN) ,  ISHIKAWA Yuichi (Yokohama City Univ., Yokohama, JPN) ,  SAKAI Ryuichi (Yokohama City Univ., Yokohama, JPN) ,  OIKAWA Masato (Yokohama City Univ., Yokohama, JPN)
Material： ACS Combinatorial Science  (ACS Comb Sci)
Volume： 18  Issue： 7  Page： 399-404  Publication year： Jul. 2016 
JST Material Number： W1756A  ISSN： 2156-8952  CODEN： ACSCCC  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *aldehyde ,  *allyl compound ,  *aliphatic alcohol ,  *unsaturated alcohol ,  *nitrile ,  *stereoselectivity ,  condensation reaction ,  oxygen heterocyclic compound ,  ligand ,  *monosaccharide ,  vinyl compound ,  Hydrolysis ,  amino acid ,  Mus musculus ,  in vivo experiment ,  *cranial nerve ,  *cyclization reaction ,  Prins reaction ,  *glucose derivatives ,  *diastereoselectivity ,  tetrahydropyran derivative ,  homoallyl alcohols ,  three-component reaction ,  Fused-Ring Compounds ,  *allyl alcohols ,  Glutamates ,  Pyrans ,  Furans ,  Myomorpha ,  aromatic aldehyde ,  phenol ether ,  aliphatic aldehyde ,  aromatic nitrile ,  olefin compound ,  alicyclic alcohol ,  monocyclic monoterpene
Semi thesaurus term： *allyl alcohol derivatives ,  glutamate ,  Pyrans ,  furans

JST classification (3)： Cyclization reaction,ring-opening reaction  (CF02050I) ,  Stereochemistry of organic reaction  (CF02130V) ,  Drugs acting on central nervous system in general  (GW03010A)

Substance index (16)： 2-Chlorobenzaldehyde ,  4-Methoxybenzaldehyde ,  Acetaldehyde ,  Benzonitrile ,  (1S)-1β-Carboxy-3-oxo-1,2,3aβ,3bα,7aα,8a-hexahydro-3H,5H-4,8-dioxa-2-azacyclopenta[a]indene-8aβ-acetic acid ,  N-[(3aR)-5β-Phenyl-2-oxo-3,3aα,5,6,7,7aα-hexahydro-2H-furo[3,2-b]pyran-7β-yl]acetamide ,  N-[(3aR)-5β-Styryl-2-oxo-3,3aα,5,6,7,7aα-hexahydro-2H-furo[3,2-b]pyran-7β-yl]acetamide ,  N-[(3aR)-5β-Styryl-2-oxo-3,3aα,5,6,7,7aα-hexahydro-2H-furo[3,2-b]pyran-7β-yl]benzamide ,  (R)-4-Pentene-1,2-diol 1-tosylate ,  N-[(2R)-2-(Tosyloxymethyl)-6β-methyltetrahydro-2H-pyran-4β-yl]acrylamide ,  Isopulegol ,  N-[(2R)-2β-(4-Methoxyphenyl)-4,7β-dimethyl-3,4,4aβ,5,6,7,8,8aα-octahydro-2H-1-benzopyran-4-yl]acetamide ,  2,2-Dimethyl-5α-vinyl-3aβ,5,6,6aβ-tetrahydrofuro[2,3-d]-1,3-dioxole-6α-ol ,  2,2-Dimethyl-5β-(3-chlorophenyl)-7β-phenyl-3aβ,3bα,6,7,7aα,8aβ-hexahydro-2H,5H-1,3,4,8-tetraoxacyclopenta[a]indene ,  4β-Hydroxy-5β-vinyltetrahydrofuran-2-one ,  (1S)-1β-Carboxy-7β-hydroxy-5β-phenyl-3-oxo-1,2,3aβ,3bα,7aα,8a-hexahydro-3H,5H-4,8-dioxa-2-azacyclopenta[a]indene-8aβ-acetic acid

Terms in the title (10)： ジアステレオ選択 ,  PRINS ,  Ritter反応 ,  CIS ,  縮合 ,  前駆体 ,  神経 ,  受容体 ,  配位子 ,  可能性