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J-GLOBAL ID：201802265161993839   Reference number：18A1107683

Initial hazard assessment of 4-benzylphenol, a structural analog of bisphenol F: Genotoxicity tests in vitro and a 28-day repeated-dose toxicity study in rats

ビスフェノールFの構造類似体である4-ベンジルフェノールの初期危険性評価:ラットにおけるin vitroおよび28日間反復投与毒性試験【JST・京大機械翻訳】

Author (11)： Igarashi Toshime (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Serizawa Hideki (BoZo Research Center Inc., 1284 Kamado, Gotennba, Shizuoka, 412-0039, Japan) ,  Kobayashi Katsumi (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Suzuki Hiroshi (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Matsumoto Mariko (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Iso Takako (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Kawamura Tomoko (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Inoue Kaoru (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Ono Atsushi (Division of Pharmaceutical, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8530, Japan) ,  Yamada Takashi (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan) ,  Hirose Akihiko (Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan)
Material： Regulatory Toxicology and Pharmacology  (Regul Toxicol Pharmacol)
Volume： 96  Page： 64-75  Publication year： 2018 
JST Material Number： T0249A  ISSN： 0273-2300  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： 4-Benzylphenol (CAS No. 101-53...

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Thesaurus term： safety ,  *toxicity test ,  hamster ,  keratosis ,  body weight ,  *in vitro experiment ,  flatness(morphology) ,  hyperplasia ,  *repeated administration ,  plastic ,  epithelium ,  screening(inspection) ,  People's Republic of China
Semi thesaurus term： 前胃 ,  有機合成 , 【Automatic Indexing@JST】

Author keywords (10)： CAS no. 101-53-1 ,  4-Benzylphenol ,  Genotoxicity ,  Repeated-dose toxicity ,  Rat ,  Gavage ,  NOAEL ,  D-value ,  Hazard class ,  Screening risk assessment

JST classification (1)： Toxicity of organic compounds  (GZ02030Y)

Terms in the title (8)： ビスフェノールF ,  類似体 ,  4-ベンジルフェノール ,  初期 ,  危険性評価 ,  ラット ,  反復投与 ,  毒性試験