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J-GLOBAL ID：201802265242411303   Reference number：18A1850747

Inhibitory Effects of S-carboxymethylcystein on Goblet Cell Proliferation in Cultured Epithelium

培養上皮における杯細胞増殖に及ぼすS-カルボキシメチルシステインの阻害効果

Author (7)： Yamaguchi Satoshi (Department of Otorhinolaryngology, Nippon Medical School Musashi Kosugi Hospital) ,  Matsune Shoji (Department of Otorhinolaryngology, Nippon Medical School Musashi Kosugi Hospital) ,  Sekine Kuwon (Department of Otorhinolaryngology, Nippon Medical School Musashi Kosugi Hospital) ,  Wakayama Nozomu (Department of Otorhinolaryngology, Nippon Medical School Musashi Kosugi Hospital) ,  Kitayama Yasuhiko (Department of Pathology, Nippon Medical School Musashi Kosugi Hospital) ,  Nakamura Yuji (Department of Pathology, Nippon Medical School Musashi Kosugi Hospital) ,  Okubo Kimihiro (Department of Otolaryngology, Nippon Medical School Hospital)
Material： Journal of Nippon Medical School  (日本医科大学雑誌)
Volume： 85  Issue： 4  Page： 215-220(J-STAGE)  Publication year： 2018 
JST Material Number： F0887A  ISSN： 1345-4676  CODEN： JNMSF5  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *otological drug ,...
Semi thesaurus term： Goblet Cells ,...

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Author keywords (5)： S-carboxymethylcystein ,  TNF-α ,  chronic sinusitis ,  goblet cell ,  nasal polyp

JST classification (2)： Basic otorhinolaryngology  (GQ01020F) ,  Basic research of drugs acting on sensory organs  (GW04060K)

Substance index (1)： Carbocysteine

Reference (21)：

• 1. Ikeda K: Pathophysiology and Treatment Strategy of Chronic Rhinosinusitis with Nasal Polyps. Practica Oto-Rhino-Laryngologica 2013; 106: 573-580.
• 2. Majima Y: Pathogenesis of mucus hypersecretion and its treatments in chronic sinusitis. Japanese Journal of Rhinology 2007; 46: 50-56.
• 3. Iida M: Immunohistochemical Analysis of Proliferating Cell Nuclear Antigen Expression in Human Nasal Polyp. Oto-rhino-laryngology Tokyo. 1998; 41: 15-20.
• 4. Furukido K: Treatment of Sinusitis with the YAMIK Sinus Catheter. Oto-rhino-laryngology Tokyo. 2003; 46: 34-40.
• 5. Ueda T: Cytokine of Paranasal Sinus Effusion Taken by the YAMIK Sinus Catheter. Oto-rhino-laryngology Tokyo. 2001; 44: 88-96.

Terms in the title (6)： 培養 ,  上皮 ,  杯細胞 ,  増殖 ,  S-カルボキシメチルシステイン ,  阻害効果