Art

J-GLOBAL ID：201802266359971531   Reference number：18A2063060

SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity

p73のSIRT2仲介不活性化は,膠芽腫の腫瘍形成性に必要である【JST・京大機械翻訳】

Author (15)： Funato Kosuke (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Funato Kosuke (Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA) ,  Hayashi Tomoatsu (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Echizen Kanae (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Negishi Lumi (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Shimizu Naomi (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Koyama-Nasu Ryo (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Nasu-Nishimura Yukiko (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Morishita Yasuyuki (Department of Human Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Tabar Viviane (Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA) ,  Todo Tomoki (Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Ino Yasushi (Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Mukasa Akitake (Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Saito Nobuhito (Department of Neurosurgery, Faculty of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan) ,  Akiyama Tetsu (Laboratory of Molecular and Genetic Information, Institute of Molecular and Cellular Biosciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan)
Material： EMBO Reports  (EMBO Rep)
Volume： 19  Issue： 11  Page： e45587  Publication year： 2018 
JST Material Number： W1261A  ISSN： 1469-221X  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Glioblastoma is one of the mos...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A2063060&from=J-GLOBAL&jstjournalNo=W1261A") }}

Thesaurus term： *inactivation ,  *glioblastoma ,  stem cell ,  deacetylation ,  *tumorigenesis ,  p53 protein ,  molecular targeting ,  transcriptional activity ,  Lys residue ,  C-terminal side ,  molecular mechanism ,  Sirtuin 2 ,  *p73 protein
Semi thesaurus term： 予後不良 , 【Automatic Indexing@JST】

Author keywords (4)： cancer stem cells ,  glioblastoma ,  p73 ,  SIRT2

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (6)： p73 ,  SIRT2 ,  仲介 ,  不活性化 ,  膠芽腫 ,  腫瘍形成