Art

J-GLOBAL ID：201802267216261406   Reference number：18A0359499

Red ginseng extracts attenuate skin inflammation in atopic dermatitis through p70 ribosomal protein S6 kinase activation

紅参抽出物はp70リボソーム蛋白質S6キナーゼ活性化を介してアトピー性皮膚炎における皮膚炎症を減弱する

Author (9)： Osada-Oka Mayuko (Food Hygiene and Environmental Health, Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan) ,  Hirai Sayaka (Food Hygiene and Environmental Health, Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan) ,  Izumi Yasukatsu (Department of Pharmacology, Osaka City University Medical School, Osaka, Japan) ,  Misumi Kazuhiro (Food Hygiene and Environmental Health, Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan) ,  Samukawa Keiichi (Department of Pharmacology, Osaka City University Medical School, Osaka, Japan) ,  Tomita Shuhei (Department of Pharmacology, Osaka City University Medical School, Osaka, Japan) ,  Miura Katsuyuki (Applied Pharmacology and Therapeutics, Osaka City University Medical School, Osaka, Japan) ,  Minamiyama Yukiko (Food Hygiene and Environmental Health, Division of Applied Life Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan) ,  Iwao Hiroshi (Department of Education, Shitennoji University, Habikino, Japan)
Material： Journal of Pharmacological Sciences (Web)  (J Pharmacol Sci (Web))
Volume： 136  Issue： 1  Page： 9-15  Publication year： 2018 
JST Material Number： U0667A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *plant preparation ,...
Semi thesaurus term： cellular signal transduction ,...

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Author keywords (5)： p70 ribosomal protein S6 kinase ,  Red ginseng ,  Atopic dermatitis ,  Basophil ,  Keratinocyte

JST classification (2)： Basic research of pharmacology of crude drugs  (GX06020J) ,  Basic dermatology  (GF01020Y)

Reference (24)：

• Siraganian RP. Mast cell signal transduction from the high-affinity IgE receptor. Curr Opin Immunol. 2003;15:639-646.
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• Kawakami T, Galli SJ. Regulation of mast-cell and basophil function and survival by IgE. Nat Rev Immunol. 2002;2:773-786.
• Harir N, Friedbichler K, Sonneck K, et al. Oncogenic kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade 2008;112: 2463-2473.
• Lusková P, Dráber P. Modulation of the Fcepsilon receptor I signaling by tyrosine kinase inhibitors: search for therapeutic targets of inflammatory and allergy diseases. Curr Pharm Des. 2004;10:1727-1737.

Terms in the title (8)： 紅参 ,  抽出物 ,  p70 ,  リボソーム蛋白質S6キナーゼ ,  活性化 ,  アトピー性皮膚炎 ,  皮膚炎症 ,  減弱