Art
J-GLOBAL ID：201802267615007686   Reference number：18A0611383

Effects of doxorubicin on sperm DNA methylation in mouse models of testicular toxicity

精巣毒性のマウスモデルにおける精子DNAメチル化に及ぼすドキソルビシンの影響【Powered by NICT】
Author (7)：
Sakai Kazuya

About Sakai Kazuya

(Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan)

About Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan

, 
Ideta-Otsuka Maky

About Ideta-Otsuka Maky

(Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan)

About Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan

, 
Saito Hirokatsu

About Saito Hirokatsu

(Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan)

About Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan

, 
Hiradate Yuki

About Hiradate Yuki

(Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan)

About Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan

, 
Hara Kenshiro

About Hara Kenshiro

(Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan)

About Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan

, 
Igarashi Katsuhide

About Igarashi Katsuhide

(Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan)

About Life Science Tokyo Advanced Research Center (L-StaR), Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan

, 
Tanemura Kentaro

About Tanemura Kentaro

(Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan)

About Laboratory of Animal Reproduction and Development, Graduate School of Agricultural Science, Tohoku University, Sendai, Miyagi, Japan


Material：
Biochemical and Biophysical Research Communications  (BBRC)

About Biochemical and Biophysical Research Communications


Volume： 498  Issue： 3  Page： 674-679  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)
Abstract/Point：
Abstract/Point
Japanese summary of the article(about several hundred characters).
All summary is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
Testicular toxicity is a frequ...
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Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
toxicity test

About toxicity test

, 
DNA methyltransferase

About DNA methyltransferase

, 
Western blotting

About Western blotting

, 
biomarker

About biomarker

, 
*spermatozoon

About spermatozoon

, 
*testis

About testis

, 
antitumor drug

About antitumor drug

, 
binding site

About binding site

, 
*toxicity

About toxicity

, 
epigenetics

About epigenetics

, 
protein

About protein

, 
amino sugar

About amino sugar

, 
quinone

About quinone

, 
glycoside(except carbohydrate)

About glycoside(except carbohydrate)

, 
polyphenol

About polyphenol

, 
deoxysugar

About deoxysugar

, 
pyranoside

About pyranoside

, 
phenol ether

About phenol ether

, 
polynuclear aromatic compound

About polynuclear aromatic compound

, 
hydroxy ketone

About hydroxy ketone

, 
polyol

About polyol


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*DNAメチル化

About DNAメチル化

, 
*マウスモデル

About マウスモデル

, 
*精巣毒性

About 精巣毒性

, 【Automatic Indexing@JST】
Author keywords (4)：
Testicular toxicity

About Testicular toxicity

, 
Sperm DNA methylation

About Sperm DNA methylation

, 
Doxorubicin

About Doxorubicin

, 
Mouse

About Mouse

JST classification (4)：
JST classification
Category name(code) classified by JST.
Chemistry,biochemistry and pathology of tumors(=neoplasms) 
(GE02030N)

About Chemistry,biochemistry and pathology of tumors(=neoplasms)

,  Biological function 
(EB03040U)

About Biological function

,  Reproductive(=genital)organs 
(EJ15020P)

About Reproductive(=genital)organs

,  Influence on animals 
(EE04040K)

About Influence on animals

Substance index (1)：
Substance index
Chemical Substance indexed to the Article.
Doxorubicin

About Doxorubicin

Terms in the title (5)：
Terms in the title
Keywords automatically extracted from the title.
精巣毒性

About 精巣毒性

, 
マウスモデル

About マウスモデル

, 
精子

About 精子

, 
DNAメチル化

About DNAメチル化

, 
ドキソルビシン

About ドキソルビシン


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