Art

J-GLOBAL ID：201802268121689115   Reference number：18A1643187

Incorporation, intracellular trafficking and processing of extracellular heparanase by mast cells: Involvement of syndecan-4-dependent pathway

肥満細胞による細胞外heparナーゼの取り込み,細胞内輸送およびプロセシング:シンデカン-4依存性経路の関与【JST・京大機械翻訳】

Author (12)： Higashi Nobuaki (Department of Biochemistry, Hoshi University School of Pharmacy, 2-4-41, Ebara, Shinagawa-ku, Tokyo, 144-8501, Japan) ,  Waki Michihiko (Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan) ,  Sudo Yukiaki (Department of Biochemistry, Hoshi University School of Pharmacy, 2-4-41, Ebara, Shinagawa-ku, Tokyo, 144-8501, Japan) ,  Suzuki Sana (Department of Biochemistry, Hoshi University School of Pharmacy, 2-4-41, Ebara, Shinagawa-ku, Tokyo, 144-8501, Japan) ,  Oku Teruaki (Department of Microbiology, Hoshi University School of Pharmacy, 2-4-41, Ebara, Shinagawa-ku, Tokyo, 144-8501, Japan) ,  Tsuiji Makoto (Department of Microbiology, Hoshi University School of Pharmacy, 2-4-41, Ebara, Shinagawa-ku, Tokyo, 144-8501, Japan) ,  Tsuji Tsutomu (Department of Microbiology, Hoshi University School of Pharmacy, 2-4-41, Ebara, Shinagawa-ku, Tokyo, 144-8501, Japan) ,  Miyagishi Makoto (Molecular Composite Medicine Research Group, Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1, Higashi, Tsukuba-city, Ibaraki, 305-8561, Japan) ,  Takahashi Katsuhiko (Department of Biochemistry, Hoshi University School of Pharmacy, 2-4-41, Ebara, Shinagawa-ku, Tokyo, 144-8501, Japan) ,  Nakajima Motowo (SBI Pharmaceuticals Co., Ltd, 1-6-1, Roppongi, Minato-ku, Tokyo, 106-6019, Japan) ,  Irimura Tatsuro (Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan) ,  Irimura Tatsuro (Division of Glycobiologics, Intractable Disease Research Center, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo, 104-8520, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 503  Issue： 4  Page： 3235-3241  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： We investigated the fate of pr...

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Thesaurus term： internalization ,  glycosaminoglycan ,  heparan sulfate ,  granule(particle) ,  heparin ,  clone ,  *mastocyte ,  recombinant protein ,  *intracellular transport ,  myeloid cell ,  enzyme ,  transfection ,  gene
Semi thesaurus term： 細胞表面 ,  *シンデカン , 【Automatic Indexing@JST】

Author keywords (6)： Heparanase ,  Mast cells ,  Heparin ,  Syndecan ,  Endocytosis ,  Secretory granules

JST classification (4)： Function of cell components  (EF03060C) ,  Enzyme in general  (EB09010D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Biological function  (EB06020T)

Terms in the title (7)： 肥満細胞 ,  取り込み ,  細胞内輸送 ,  プロセシング ,  シンデカン ,  依存性 ,  経路