Art

J-GLOBAL ID：201802268156518305   Reference number：18A0604825

Combination of PNPLA3 and TLL1 polymorphism can predict advanced fibrosis in Japanese patients with nonalcoholic fatty liver disease

PNPLA3とTLL1遺伝子多型の組合わせは非アルコール性脂肪肝疾患の日本人患者における進行性線維化を予測し得る

Author (20)： SEKO Yuya (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  YAMAGUCHI Kanji (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  MIZUNO Naoki (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  OKUDA Keiichiro (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  TAKEMURA Masashi (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  TAKETANI Hiroyoshi (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  HARA Tasuku (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  UMEMURA Atsushi (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  NISHIKAWA Taichiro (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  MORIGUCHI Michihisa (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  YASUI Kohichiroh (Kyoto Prefectural Univ. Medicine, Kyoto, JPN) ,  KAMAGUCHI Mai (Kyoto Second Red Cross Hospital, Kyoto, JPN) ,  NISHIOJI Kenichi (Kyoto Second Red Cross Hospital, Kyoto, JPN) ,  MOCHIZUKI Naomi (Kyoto Second Red Cross Hospital, Kyoto, JPN) ,  KOBAYASHI Masao (Kyoto Second Red Cross Hospital, Kyoto, JPN) ,  MORI Kojiroh (Nara City Hospital, Nara, JPN) ,  TANAKA Saiyu (Nara City Hospital, Nara, JPN) ,  MATSUURA Kentaro (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  TANAKA Yasuhito (Nagoya City Univ. Graduate School of Medical Sci., Nagoya, JPN) ,  ITOH Yoshito (Kyoto Prefectural Univ. Medicine, Kyoto, JPN)
Material： Journal of Gastroenterology  (J Gastroenterol)
Volume： 53  Issue： 3  Page： 438-448  Publication year： 2018 
JST Material Number： Z0748A  ISSN： 0944-1174  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *Non alcoholic fatty liver disease ,...

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JST classification (2)： Digestive system diseases  (GH03000W) ,  Genetic variation  (EC01030Y)

Reference (50)：

• Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology. 2012;55:2005-23.
• Watanabe S, Hashimoto E, Ikejima K, et al. Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. J Gastroenterol. 2015;50(4):364-77.
• Tateishi R, Okanoue T, Fujiwara N, et al. Clinical characteristics, treatment, and prognosis of non-B, non-C hepatocellular carcinoma: a large retrospective multicenter cohort study. J Gastroenterol. 2015;50(3):350-60.
• Angulo P, Kleiner DE, Dam-Larsen S, et al. Liver Fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease. Gastroenterology. 2015;149(2):389-97.
• Seko Y, Sumida Y, Tanaka S, et al. Predictors of malignancies and overall mortality in Japanese patients with biopsy-proven non-alcoholic fatty liver disease. Hepatol Res. 2015;45(7):728-38.

Terms in the title (8)： PNPLA3 ,  遺伝子多型 ,  組合わせ ,  非アルコール性脂肪肝疾患 ,  日本人 ,  患者 ,  線維化 ,  予測