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J-GLOBAL ID：201802269298207015   Reference number：18A0420533

Indirubin 3′-oxime inhibits anticancer agent-induced YB-1 nuclear translocation in HepG2 human hepatocellular carcinoma cells

インジルビン3′-オキシムはH epG2ヒト肝細胞癌細胞における抗腫瘍剤誘発YB-1の核移行を阻害する【Powered by NICT】

Author (8)： Tanaka Toru (Department of Biochemistry, School of Pharmacy, Nihon University, Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Ohashi Sachiyo (Department of Biochemistry, School of Pharmacy, Nihon University, Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Saito Hiroaki (Department of Bio-organic Chemistry, School of Pharmacy, Nihon University, Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Wada Taira (Department of Health Science, School of Pharmacy, Nihon University, Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Aoyama Tadashi (Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, Kanda Surugadai, Tokyo 101-8308, Japan) ,  Ichimaru Yoshimi (Department of Bio-organic Chemistry, School of Pharmacy, Nihon University, Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Miyairi Shinichi (Department of Bio-organic Chemistry, School of Pharmacy, Nihon University, Narashinodai, Funabashi, Chiba 274-8555, Japan) ,  Kobayashi Shunsuke (Department of Biochemistry, School of Pharmacy, Nihon University, Narashinodai, Funabashi, Chiba 274-8555, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 496  Issue： 1  Page： 7-11  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Hepatocellular carcinoma (HCC)...

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Thesaurus term： translocation (genetics) ,  *antitumor drug ,  *human ,  *hepatoma ,  gene expression ,  P glycoprotein ,  Cytoplasm ,  antitumor action ,  Cell Line, Tumor ,  *Stem cell, Human ,  MDR1 gene ,  *nuclear translocation ,  *Y-Box-Binding Protein 1 ,  cellular genetic phenomenon ,  molecular genetic phenomenon ,  transmembrane protein
Semi thesaurus term： 癌治療 ,  阻害剤 , 【Automatic Indexing@JST】

Author keywords (5)： YB-1 ,  Nuclear translocation ,  Inhibitor ,  Indirubin 3′-oxime ,  HepG2

JST classification (2)： Cell physiology in general  (EF02010S) ,  Function of cell components  (EF03060C)

Terms in the title (9)： インジルビン ,  オキシム ,  ヒト肝細胞 ,  癌細胞 ,  抗腫瘍剤 ,  誘発 ,  YB-1 ,  核移行 ,  阻害