Art

J-GLOBAL ID：201802269855613404   Reference number：18A1499996

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

エキソソームのPD-L1は免疫抑制に関与し,抗PD-1応答と関連する

Author (45)： CHEN Gang (Univ. Pennsylvania, PA, USA) ,  ZHANG Wei (Univ. Pennsylvania, PA, USA) ,  WU Min (Univ. Pennsylvania, PA, USA) ,  YANG Jiegang (Univ. Pennsylvania, PA, USA) ,  WANG Beike (Univ. Pennsylvania, PA, USA) ,  ZHONG Wenqun (Univ. Pennsylvania, PA, USA) ,  WU Bin (Univ. Pennsylvania, PA, USA) ,  GUAN Lei (Univ. Pennsylvania, PA, USA) ,  LU Youtao (Univ. Pennsylvania, PA, USA) ,  KIM Junhyong (Univ. Pennsylvania, PA, USA) ,  GUO Wei (Univ. Pennsylvania, PA, USA) ,  HUANG Alexander C. (Univ. Pennsylvania, PA, USA) ,  MCGETTIGAN Suzanne (Univ. Pennsylvania, PA, USA) ,  MITCHELL Tara C. (Univ. Pennsylvania, PA, USA) ,  SCHUCHTER Lynn M. (Univ. Pennsylvania, PA, USA) ,  ZHANG Wei (Wuhan Univ., Wuhan, CHN) ,  YU Zili (Wuhan Univ., Wuhan, CHN) ,  YANG Jiegang (Wuhan Univ., Wuhan, CHN) ,  WANG Beike (Wuhan Univ., Wuhan, CHN) ,  XIA Houfu (Wuhan Univ., Wuhan, CHN) ,  MAN Qiwen (Wuhan Univ., Wuhan, CHN) ,  ZHONG Wenqun (Wuhan Univ., Wuhan, CHN) ,  XIONG Xuepeng (Wuhan Univ., Wuhan, CHN) ,  ZHAO Yifang (Wuhan Univ., Wuhan, CHN) ,  ZHANG Gao (Wistar Inst., PA, USA) ,  SOMASUNDARAM Rajasekharan (Wistar Inst., PA, USA) ,  HERLYN Meenhard (Wistar Inst., PA, USA) ,  XU Wei (Univ. Pennsylvania, PA, USA) ,  ANTELO Leonardo F. (Univ. Pennsylvania, PA, USA) ,  SUN Honghong (Univ. Pennsylvania, PA, USA) ,  LIU Xiaoming (Univ. Pennsylvania, PA, USA) ,  LI Ting (Univ. Pennsylvania, PA, USA) ,  LIU Shujing (Univ. Pennsylvania, PA, USA) ,  YANG Ruifeng (Univ. Pennsylvania, PA, USA) ,  DONG Liyun (Univ. Pennsylvania, PA, USA) ,  CHEN Youhai H. (Univ. Pennsylvania, PA, USA) ,  KARAKOUSIS Giorgos C. (Univ. Pennsylvania, PA, USA) ,  XU Xiaowei (Univ. Pennsylvania, PA, USA) ,  GUAN Lei (Xi’an Jiaotong Univ., Xi’an, CHN) ,  LI Ting (Xi’an Jiaotong Univ., Xi’an, CHN) ,  RADHAKRISHNAN Ravi (Univ. Pennsylvania, PA, USA) ,  MILLS Gordon (Univ. Texas MD Anderson Cancer Center, TX, USA) ,  LU Yiling (Univ. Texas MD Anderson Cancer Center, TX, USA) ,  DONG Haidong (Mayo Clinic, MN, USA) ,  WHERRY E. John (Univ. Pennsylvania, PA, USA)
Material： Nature (London)  (Nature (Lond))
Volume： 560  Issue： 7718  Page： 382-386  Publication year： Aug. 16, 2018 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： T cell ,  receptor ,  tumor ,  therapy ,  interaction ,  *immunosuppression ,  interferon gamma ,  patient ,  tumor cell ,  Immune Evasion ,  anti PD-1 antibody ,  *Programmed Cell Death 1 Receptor ,  *Antigens, CD274 ,  *Exosomes ,  *reaction ,  *immune response ,  *suppression and control
Semi thesaurus term： 奏功率 , 【Automatic Indexing@JST】

JST classification (2)： Tumor immunity  (ED03040A) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (5)： エキソソーム ,  PD-L1 ,  免疫抑制 ,  PD-1 ,  応答