Art

J-GLOBAL ID：201802270026080574   Reference number：18A2211282

CD44v-dependent upregulation of xCT is involved in the acquisition of cisplatin-resistance in human lung cancer A549 cells

XCTのCD44V依存性上方制御はヒト肺癌A549細胞におけるシスプラチン耐性獲得に関与する【JST・京大機械翻訳】

Author (8)： Horibe Sayo (Laboratory of Medical Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe, 658-8558, Japan) ,  Kawauchi Shoji (Educational Center for Clinical Pharmacy, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe, 658-8558, Japan) ,  Tanahashi Toshihito (Laboratory of Medical Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe, 658-8558, Japan) ,  Tanahashi Toshihito (Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan) ,  Sasaki Naoto (Laboratory of Medical Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe, 658-8558, Japan) ,  Mizuno Shigeto (Laboratory of Medical Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe, 658-8558, Japan) ,  Mizuno Shigeto (Endoscopy Department, Kindai University Nara Hospital, 1248-1, Otoda-cho, Ikoma 630-0293, Japan) ,  Rikitake Yoshiyuki (Laboratory of Medical Pharmaceutics, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe, 658-8558, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 507  Issue： 1-4  Page： 426-432  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 短報  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Cisplatin (CDDP) is widely use...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A2211282&from=J-GLOBAL&jstjournalNo=B0118A") }}

Thesaurus term： *human ,  sensitivity ,  Drug Resistance ,  *Up-Regulation ,  siRNA ,  *lung tumor ,  mRNA ,  tumor cell ,  therapeutic planning ,  cell migration ,  *A549 cell ,  overexpression ,  cystine transporter ,  CD44v ,  *platinum complex ,  *antitumor drug ,  *ammine complex ,  *chloro complex
Semi thesaurus term： *cisplatin , 【Automatic Indexing@JST】

Author keywords (5)： Cancer stem cell ,  CD44v ,  Cisplatin ,  Drug resistance ,  xCT

JST classification (2)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N)

Terms in the title (9)： xCT ,  CD44v ,  依存性 ,  上方制御 ,  ヒト ,  肺癌 ,  A549細胞 ,  シスプラチン耐性 ,  獲得