Art

J-GLOBAL ID：201802272322926491   Reference number：18A0961911

Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin

シプロフロキサシンとアトルバスタチンの同時投与による薬物誘発横紋筋融解症マウスモデルの確立【JST・京大機械翻訳】

Author (5)： Matsubara Akiko (Department of Drug Safety Sciences, Division of Clinical Pharmacology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan) ,  Oda Shingo (Department of Drug Safety Sciences, Division of Clinical Pharmacology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan) ,  Akai Sho (Department of Drug Safety Sciences, Division of Clinical Pharmacology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan) ,  Tsuneyama Koichi (Department of Pathology and Laboratory Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-5 Kuramoto-cho, Tokushima, 770-8503, Japan) ,  Yokoi Tsuyoshi (Department of Drug Safety Sciences, Division of Clinical Pharmacology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan)
Material： Toxicology Letters  (Toxicol Lett)
Volume： 291  Page： 184-193  Publication year： 2018 
JST Material Number： E0034B  ISSN： 0378-4274  CODEN： TOLED5  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Rhabdomyolysis is one of the s...

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Thesaurus term： pathogenesis ,  *Rhabdomyolysis ,  Creatine Kinase ,  myoglobin ,  patient ,  mRNA ,  Plasma ,  plasma concentration ,  aspartate aminotransferase ,  histological diagnosis ,  oral administration ,  *mouse model ,  aliphatic amine ,  aliphatic alcohol ,  aliphatic carboxylic acid ,  aminoalcohol ,  aminocarboxylic acid ,  primary amine ,  secondary alcohol ,  hydroxy acid ,  alicyclic compound ,  nitrogen heterocyclic compound ,  aromatic fluorine compound ,  polynuclear aromatic compound ,  keto acid

Author keywords (4)： Drug-induced rhabdomyolysis ,  New quinolone antibacterial drug ,  Acute kidney injury ,  Drug-drug interactions

JST classification (1)： Toxicity of organic compounds  (GZ02030Y)

Substance index (3)： Statine ,  Atorvastatin ,  Ciprofloxacin

Terms in the title (7)： シプロフロキサシン ,  アトルバスタチン ,  同時投与 ,  薬物 ,  誘発 ,  横紋筋融解症 ,  マウスモデル