Art

J-GLOBAL ID：201802272846668672   Reference number：18A0975341

Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A 2 in a spatial-specific manner

オリゴマーアミロイドβは空間特異的様式における脳サイトゾル及びカルシウム非依存性ホスホリパーゼA2のMAPK仲介活性化を誘導する【JST・京大機械翻訳】

Author (8)： Palavicini Juan Pablo (Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, USA) ,  Wang Chunyan (Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, USA) ,  Chen Linyuan (Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, USA) ,  Hosang Kristen (Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, USA) ,  Wang Jianing (Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, USA) ,  Tomiyama Takami (Department of Translational Neuroscience, Osaka City University Graduate School of Medicine, Osaka, Japan) ,  Mori Hiroshi (Department of Clinical Neuroscience, Osaka City University Graduate School of Medicine, Osaka, Japan) ,  Han Xianlin (Center for Metabolic Origins of Disease, Sanford Burnham Prebys Medical Discovery Institute, Orlando, USA)
Material： Acta Neuropathologica Communications (Web)
Volume： 5  Issue： 1  Page： 56  Publication year： 2017 
JST Material Number： U7296A  ISSN： 2051-5960  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Alzheimer’s disease (AD) is hi...

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Thesaurus term： Lipid Metabolism ,  oxidative stress ,  solubility (property) ,  *Cytosol ,  Alzheimer Disease ,  amyloid plaque ,  *oligomer ,  active oxygen ,  *MAP kinase ,  Pathology ,  phosphorylation ,  pathogenesis ,  *amyloid beta-protein ,  *phospholipase A2 ,  *Amyloid ,  *glycoprotein ,  *animal protein
Semi thesaurus term： 神経変性 , 【Automatic Indexing@JST】

Author keywords (6)： Alzheimer’s disease ,  Amyloid-beta ,  Fatty acid ,  Lysophospholipid ,  Phospholipase A2 ,  Oxidative stress

JST classification (2)： Basic neurology  (GN01020W) ,  Cell physiology in general  (EF02010S)

Reference (137)：

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Terms in the title (10)： オリゴマー ,  アミロイドβ ,  様式 ,  脳 ,  サイトゾル ,  カルシウム非依存性ホスホリパーゼA2 ,  MAPK ,  仲介 ,  活性化 ,  誘導