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J-GLOBAL ID：201802273966354747   Reference number：18A0607484

Epigenetic down-regulation of SOX2 is an independent poor prognostic factor for hypopharyngeal cancers

SOX2の後成的ダウンレギュレーションは下咽頭癌の独立した予後不良因子である【Powered by NICT】

Author (13)： Avincsal Mehmet Ozgur (Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Avincsal Mehmet Ozgur (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Jimbo Naoe (Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Fujikura Kohei (Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Shinomiya Hirotaka (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Otsuki Naoki (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Morimoto Koichi (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Furukawa Tatsuya (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Morita Naruhiko (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Maehara Ritsuko (Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Itoh Tomoo (Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Nibu Ken-ichi (Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Zen Yoh (Department of Diagnostic Pathology, Kobe University Graduate School of Medicine, Kobe, Japan)
Material： Histopathology
Volume： 72  Issue： 5  Page： 826-837  Publication year： 2018 
JST Material Number： W2598A  ISSN： 0309-0167  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： AIMS: We recently reported tha...

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Thesaurus term： Methylation ,  *Down-Regulation ,  esophageal tumor ,  squamous cell carcinoma ,  immunostaining ,  allele ,  Multivariate Analysis ,  polymerase chain reaction ,  Gene Silencing ,  promoter (genetics) ,  patient ,  *poor prognosis factor
Semi thesaurus term： 全生存率 ,  *予後不良 ,  臨床病理学的特徴 , 【Automatic Indexing@JST】

Author keywords (4)： methylation ,  prognosis ,  SOX2 ,  squamous cell carcinoma

JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Tumors(=neoplasms)of female genitalia and fetus  (GS04000K)

Terms in the title (4)： Sox2 ,  ダウンレギュレーション ,  下咽頭癌 ,  予後不良因子