Art

J-GLOBAL ID：201802274327250736   Reference number：18A0053265

Randomized, double-blind, phase III trial of palonosetron versus granisetron in the triplet regimen for preventing chemotherapy-induced nausea and vomiting after highly emetogenic chemotherapy: TRIPLE study

高催嘔吐性の化学療法後の化学療法誘導性吐き気および嘔吐を防ぐための三重レジメンにおけるパロノセトロン対グラニセトロンの無作為化,二重盲検,第III相試験:TRIPLE研究

Author (22)： SUZUKI K. (Shizuoka Cancer Center, Shizuoka) ,  SUZUKI K. (Cancer Inst. Hospital of the Japanese Foundation for Cancer Res., Tokyo) ,  YAMANAKA T. (Yokohama City Univ. School of Medicine, Yokohama) ,  HASHIMOTO H. (National Cancer Center Hospital, Tokyo) ,  SHIMADA Y. (National Cancer Center Hospital, Tokyo) ,  ARATA K. (Shizuoka Cancer Center, Shizuoka) ,  MATSUI R. (National Cancer Center Hospital East, Chiba) ,  GOTO K. (National Cancer Center Hospital East, Chiba) ,  TAKIGUCHI T. (Cancer Inst. Hospital of the Japanese Foundation for Cancer Res., Tokyo) ,  OHYANAGI F. (Cancer Inst. Hospital of the Japanese Foundation for Cancer Res., Tokyo) ,  KOGURE Y. (NHO Shikoku Cancer Center, Ehime) ,  NOGAMI N. (NHO Shikoku Cancer Center, Ehime) ,  NAKAO M. (Osaka City General Hospital, Osaka) ,  TAKEDA K. (Osaka City General Hospital, Osaka) ,  AZUMA K. (Tokyo Medical Univ. Hospital, Tokyo) ,  NAGASE S. (Tokyo Medical Univ. Hospital, Tokyo) ,  HAYASHI T. (NHO Kyushu Cancer Center, Fukuoka) ,  FUJIWARA K. (Kindai Univ. Hospital, Osaka) ,  SHIMADA T. (Teikyo Univ. Hospital, Tokyo) ,  SEKI N. (Teikyo Univ. Hospital, Tokyo) ,  YAMAMOTO N. (Shizuoka Cancer Center, Shizuoka) ,  YAMAMOTO N. (Wakayama Medical Univ., Wakayama, JPN)
Material： Annals of Oncology  (Ann Oncol)
Volume： 27  Issue： 8  Page： 1601-1606  Publication year： Aug. 2016 
JST Material Number： W0107A  ISSN： 0923-7534  CODEN： ANONE2  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *antiemetic ,...
Semi thesaurus term： Drug Therapy, Combination

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JST classification (1)： Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Substance index (4)： Aprepitant ,  Granisetron ,  Dexamethasone sodium phosphate ,  Palonosetron

Reference (17)：

• Kaizer L , Warr D , Hoskins P et al. Effect of schedule and maintenance on the antiemetic efficacy of ondansetron combined with dexamethasone in acute and delayed nausea and emesis in patients receiving moderately emetogenic chemotherapy: a phase III trial by the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 1994; 12: 1050-1057.
• Latreille J , Pater J , Johnston D et al. Use of dexamethasone and granisetron in the control of delayed emesis for patients who receive highly emetogenic chemotherapy. National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 1998; 16: 1174-1178.
• Hesketh PJ , Grunberg SM , Gralla RJ et al. The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin-the Aprepitant Protocol 052 Study Group. J Clin Oncol 2003; 21: 4112-4119.
• Poli-Bigelli S , Rodrigues-Pereira J , Carides AD et al. Addition of the neurokinin 1 receptor antagonist aprepitant to standard antiemetic therapy improves control of chemotherapy-induced nausea and vomiting. Results from a randomized, double-blind, placebo-controlled trial in Latin America. Cancer 2003; 97: 3090-3098.
• Basch E , Prestrud AA , Hesketh PJ et al. Antiemetics: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol 2011; 29: 4189-4198.

Terms in the title (10)： 嘔吐 ,  化学療法 ,  吐き気 ,  三重 ,  レジメン ,  パロノセトロン ,  グラニセトロン ,  二重盲検 ,  第III相試験 ,  研究