Art

J-GLOBAL ID：201802275263170407   Reference number：18A0257019

A longitudinal DTI and histological study of the spinal cord reveals early pathological alterations in G93A-SOD1 mouse model of amyotrophic lateral sclerosis

脊髄の縦DTIおよび組織学的研究は筋萎縮性側索硬化症のG93A-SOD1マウスモデルにおける初期病理学的変化を明らかにする【Powered by NICT】

Author (18)： Marcuzzo Stefania (Neurology IV -Neuroimmunology and Neuromuscular Diseases Unit, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Bonanno Silvia (Neurology IV -Neuroimmunology and Neuromuscular Diseases Unit, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Bonanno Silvia (PhD Program in Neuroscience, University of Milano-Bicocca, Milan 20126, Italy) ,  Figini Matteo (Scientific Department, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Scotti Alessandro (Scientific Department, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Zucca Ileana (Scientific Department, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Minati Ludovico (Scientific Department, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Riva Nilo (Neuropathology Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan 20132, Italy) ,  Domi Teuta (Neuropathology Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan 20132, Italy) ,  Fossaghi Andrea (Neuropathology Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan 20132, Italy) ,  Quattrini Angelo (Neuropathology Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Milan 20132, Italy) ,  Galbardi Barbara (Scientific Department, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  D'Alessandro Sara (Neurology IV -Neuroimmunology and Neuromuscular Diseases Unit, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Bruzzone Maria Grazia (Neuroradiology, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Garcia-Verdugo Jose Manuel (Unidad de Neurobiologia comparada, Universidad de Valencia, Paterna, Valencia 46980, Spain) ,  Moreno-Manzano Victoria (Neuronal and Tissue Regeneration Laboratory, Centro de Investigacion Principe Felipe, Valencia 46012, Spain) ,  Mantegazza Renato (Neurology IV -Neuroimmunology and Neuromuscular Diseases Unit, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy) ,  Bernasconi Pia (Neurology IV -Neuroimmunology and Neuromuscular Diseases Unit, Fondazione Istituto Neurologico “Carlo Besta”, Milan 20133, Italy)
Material： Experimental Neurology  (Exp Neurol)
Volume： 293  Page： 43-52  Publication year： 2017 
JST Material Number： A0094B  ISSN： 0014-4886  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Amyotrophic lateral sclerosis ...

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Thesaurus term： mitochondria ,  motor nerve ,  axon ,  dysfunction ,  *amyotrophic lateral sclerosis ,  *spinal cord ,  *pathology ,  human(primates) ,  white matter ,  motor area ,  grey matter ,  NMR imaging
Semi thesaurus term： 神経変性疾患 ,  神経変性 ,  *スーパーオキシドジスムターゼ1 , 【Automatic Indexing@JST】

Author keywords (6)： Amyotrophic lateral sclerosis ,  G93A-SOD1 mice ,  Magnetic resonance imaging ,  Electron microscopy ,  Axon degeneration ,  Motor neuron diseases

JST classification (2)： Nervous system diseases  (GN03000O) ,  Basic neurology  (GN01020W)

Terms in the title (10)： 脊髄 ,  縦 ,  DTI ,  組織学 ,  研究 ,  筋萎縮性側索硬化症 ,  SOD1 ,  マウスモデル ,  初期 ,  病理学