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J-GLOBAL ID：201802276914443370   Reference number：18A0139809

Distinct B subunits of PP2A regulate the NF-κB signalling pathway through dephosphorylation of IKKβ, IκBα and RelA

PP2Aの異なるBサブユニットはIKKβ,IκBαとRelAの脱リン酸化を通したNF-κBシグナル伝達経路を調節する【Powered by NICT】

Author (7)： Tsuchiya Yoshihiro (Laboratory of Biomedical Chemistry, Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Japan) ,  Osaki Keiko (Laboratory of Biomedical Chemistry, Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Japan) ,  Kanamoto Mayu (Laboratory of Biomedical Chemistry, Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Japan) ,  Nakao Yuki (Laboratory of Biomedical Chemistry, Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Japan) ,  Takahashi Ena (Laboratory of Biomedical Chemistry, Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Japan) ,  Higuchi Toru (Laboratory of Biomedical Chemistry, Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Japan) ,  Kamata Hideaki (Laboratory of Biomedical Chemistry, Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Japan)
Material： FEBS Letters  (for the Rapid Publication of Short Reports in Biochemistry, Biophysics)
Volume： 591  Issue： 24  Page： 4083-4094  Publication year： 2017 
JST Material Number： D0575A  ISSN： 0014-5793  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： PP2A is composed of a scaffold...

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Thesaurus term： holoenzyme ,  dimer ,  *dephosphorylation ,  complex (substance) ,  *NF-kappaB ,  serine/threonine specific protein phosphatase ,  trimer ,  catalyst ,  Proteins ,  *subunit ,  cell response ,  *I kappa B kinase beta ,  *phosphoprotein phosphatase 2A ,  *Transcription Factor RelA
Semi thesaurus term： p65 ,  *RelA , 【Automatic Indexing@JST】

Author keywords (3)： NF-kappa B ,  protein phosphatase ,  protein phosphatase 2 A (PP2A)

JST classification (2)： Gene expression  (EC02040Q) ,  Cell physiology in general  (EF02010S)

Terms in the title (9)： PP2A ,  サブユニット ,  IKKβ ,  IκBα ,  RelA ,  脱リン酸化 ,  NF-κB ,  シグナル伝達経路 ,  調節