Art

J-GLOBAL ID：201802277166362703   Reference number：18A0225047

Oral Administration of Glucosamine Improves Vascular Endothelial Function by Modulating Intracellular Redox State

グルコサミンの経口投与は細胞内レドックス状態を調節することによって血管内皮機能を改善する

Author (5)： Katoh Atsushi (Department of Cardiology, Kurume University Medical Center) ,  Kai Hisashi (Department of Cardiology, Kurume University Medical Center) ,  Harada Haruhito (Department of Cardiology, Kurume University Medical Center) ,  Niiyama Hiroshi (Department of Cardiology, Kurume University Medical Center) ,  Ikeda Hisao (Department of Physical Therapy, Faculty of Fukuoka Medical Technology, Teikyo University)
Material： International Heart Journal  (Int Heart J)
Volume： 58  Issue： 6  Page： 926-932(J-STAGE)  Publication year： 2017 
JST Material Number： Z0752A  ISSN： 1349-2365  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： Vasodilation ,...

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Author keywords (2)： Glutathione ,  Flow-mediated vasodilation

JST classification (1)： Clinical application of vasoactive drugs and hypotensive drugs  (GW07050U)

Substance index (2)： Glutathione ,  Glucosamine

Reference (36)：

• 1. Crolle G, D'Este E. Glucosamine sulphate for the management of arthrosis: a controlled clinical investigation. Curr Med Res Opin 1980; 7: 104-9.
• 2. Hua J, Sakamoto K, Nagaoka I. Inhibitory actions of glucosamine, a therapeutic agent for osteoarthritis, on the functions of neutrophils. J Leukoc Biol 2002; 71: 632-40.
• 3. Hua J, Suguro S, Iwabuchi K, Tsutsumi-Ishii Y, Sakamoto K, Nagaoka I. Glucosamine, a naturally occurring amino monosaccharide, suppresses the ADP-mediated platelet activation in humans. Inflamm Res 2004; 53: 680-8.
• 4. Duan W, Paka L, Pillarisetti S. Distinct effects of glucose and glucosamine on vascular endothelial and smooth muscle cells: evidence for a protective role for glucosamine in atherosclerosis. Cardiovasc Diabetol 2005; 4: 16.
• 5. Pocobelli G, Kristal AR, Patterson RE, et al. Total mortality risk in relation to use of less-common dietary supplements. Am J Clin Nutr 2010; 91: 1791-800.

Terms in the title (5)： グルコサミン ,  経口投与 ,  レドックス ,  調節 ,  血管内皮機能