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J-GLOBAL ID：201802277528619572   Reference number：18A1891322

ヒト-動物キメラの可能性と重要性

Author (3)： MASAKI HIDEKI (東大 医科研 幹細胞治療部門) ,  NAKAUCHI HIROMITSU (東大 医科研 幹細胞治療部門) ,  NAKAUCHI HIROMITSU (Stanford Univ. School of Medicine)
Material： Labio 21  (ラビオ)
Issue： 74  Page： 13-16  Publication year： Oct. 01, 2018 
JST Material Number： L7288A  ISSN： 1345-9147  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *chimera ,...
Semi thesaurus term： human iPS cell ,...

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JST classification (2)： Research and development  (GA01030U) ,  Laboratry organisms  (EA03070Y)

Reference (17)：

• Sekiya, S. & Suzuki, A. Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature 475, 390-393 (2011).
• Suzuki, N. et al. Generation of Engraftable Hematopoietic Stem Cells From Induced Pluripotent Stem Cells by Way of Teratoma Formation. Mol Ther 21, 1424-1431 (2013).
• Kobayashi, T. et al. Generation of Rat Pancreas in Mouse by Interspecific Blastocyst Injection of Pluripotent Stem Cells. Cell 142, 787-799 (2010).
• Usui, J. et al. Generation of Kidney from Pluripotent Stem Cells via Blastocyst Complementation. The American Journal of Pathology 180, 2417-2426 (2012).
• Yamaguchi, T. et al. Interspecies organogenesis generates autologous functional islets. Nature 542, 191-196 (2017).

Terms in the title (5)： ヒト ,  動物 ,  キメラ ,  可能性 ,  重要性