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J-GLOBAL ID：201802277981995540   Reference number：18A0751483

A spontaneously immortalized Schwann cell line from aldose reductase-deficient mice as a useful tool for studying polyol pathway and aldehyde metabolism

ポリオール経路とアルデヒド代謝を研究するための有用なツールとしてのアルドースレダクターゼ欠損マウス由来の自発的不死化Schwann細胞株【JST・京大機械翻訳】

Author (12)： Niimi Naoko (Diabetic Neuropathy Project, Department of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Yako Hideji (Diabetic Neuropathy Project, Department of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Takaku Shizuka (Diabetic Neuropathy Project, Department of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Kato Hiroshi (Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan) ,  Matsumoto Takafumi (Sumitomo Dainippon Pharma Co., Ltd., Osaka, Japan) ,  Nishito Yasumasa (Basic Technology Research Center, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan) ,  Watabe Kazuhiko (Department of Medical Technology, Faculty of Health Sciences, Kyorin University, Tokyo, Japan) ,  Ogasawara Saori (Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Mizukami Hiroki (Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Yagihashi Soroku (Department of Pathology and Molecular Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan) ,  Chung Sookja K. (School of Biomedical Sciences, Research Center of Heart, Brain, Hormone and Healthy Aging and State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong SAR, China) ,  Sango Kazunori (Diabetic Neuropathy Project, Department of Sensory and Motor Systems, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan)
Material： Journal of Neurochemistry  (J Neurochem)
Volume： 144  Issue： 6  Page： 710-722  Publication year： 2018 
JST Material Number： B0504B  ISSN： 0022-3042  CODEN： JONRA  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： The increased glucose flux int...

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Thesaurus term： neurotrophic factor ,  peripheral nerve ,  Phenotype ,  pathogenesis ,  *aldehyde ,  Up-Regulation ,  cell culture ,  diabetic neuropathy ,  Down-Regulation ,  Pathology ,  *Schwann cell ,  mRNA expression ,  microarray ,  Dorsal root ganglia ,  *polyol pathway ,  factor ,  bioactive factor ,  Diabetes Mellitus ,  complication

Author keywords (6)： aldose reductase ,  C57BL/6 mice ,  cell culture ,  polyol pathway ,  reactive aldehydes ,  Schwann cells

JST classification (1)： Cell physiology in general  (EF02010S)

Terms in the title (11)： ポリオール経路 ,  アルデヒド ,  代謝 ,  研究 ,  ツール ,  アルドースレダクターゼ ,  欠損 ,  マウス ,  不死化 ,  Schwann細胞 ,  株