Art

J-GLOBAL ID：201802278586085226   Reference number：18A1870774

The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection

BRCA1およびBARD1腫瘍抑制因子のBRCTドメインは相同性指向修復および停止フォーク保護を特異的に調節する【JST・京大機械翻訳】

Author (24)： Billing David (Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Billing David (Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Horiguchi Michiko (Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Horiguchi Michiko (Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Wu-Baer Foon (Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Wu-Baer Foon (Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Taglialatela Angelo (Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Leuzzi Giuseppe (Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Nanez Silvia Alvarez (Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Jiang Wenxia (Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Jiang Wenxia (Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Zha Shan (Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Zha Shan (Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Zha Shan (Department of Pediatrics, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Zha Shan (Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Szabolcs Matthias (Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Szabolcs Matthias (Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Lin Chyuan-Sheng (Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Lin Chyuan-Sheng (Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Ciccia Alberto (Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Ciccia Alberto (Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Baer Richard (Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Baer Richard (Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA) ,  Baer Richard (Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY 10032, USA)
Material： Molecular Cell  (Mol Cell)
Volume： 72  Issue： 1  Page： 127-139.e8  Publication year： 2018 
JST Material Number： W1167A  ISSN： 1097-2765  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The BRCA1 tumor suppressor pre...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A1870774&from=J-GLOBAL&jstjournalNo=W1167A") }}

Thesaurus term： *homology(characteristic) ,  *tumor ,  phosphoric acid ,  genome ,  variation(biology) ,  tumorigenesis ,  protein ,  mutation ,  completeness
Semi thesaurus term： ゲノム不安定性 ,  複製フォーク ,  *腫瘍抑制 ,  *ドメイン構造 ,  *腫瘍抑制因子 ,  *BRCA1蛋白質 , 【Automatic Indexing@JST】

Author keywords (9)： BARD1 ,  BRCA1 ,  familial breast cancer ,  tumor suppression ,  BRCT domain ,  genome instability ,  stalled replication forks ,  poly(ADP-ribose) ,  DNA break repair

JST classification (2)： Molecular genetics in general  (EC02010J) ,  Biological function  (EB03040U)

Terms in the title (7)： BRCA1 ,  腫瘍抑制因子 ,  ドメイン ,  相同性 ,  修復 ,  フォーク ,  調節