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J-GLOBAL ID：201802279681595280   Reference number：18A1129552

Synthesis of epigallocatechin trimer, (epigallocatechin)₂-epicatechin, and (epigallocatechin)₂-catechin via a Lewis acid mediated one-pot condensation and their antitumor activities in prostate cancer cells

Lewis酸媒介ワンポット縮合によるエピガロカテキン三量体,(エピガロカテキン)2-エピカテキンおよび(エピガロカテキン)2-カテキンの合成および前立腺癌細胞におけるそれらの抗腫瘍活性【JST・京大機械翻訳】

Author (12)： Ichikawa Mikihiro (Graduate School of Agriculture, Sciences of Functional Foods, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Yamamoto Shinya (Graduate School of Science and Technology, Department of Agriculture, Division of Food Science and Biotechnology, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Ishihara Chisato (Graduate School of Science and Technology, Department of Biomedical Engineering, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Nonobe Shuhei (Graduate School of Science and Technology, Department of Biomedical Engineering, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Hattori Yasunao (Centre for Instrumental Analysis, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto, 607-8412, Japan) ,  Umezawa Koji (Graduate School of Science and Technology, Department of Biomedical Engineering, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Umezawa Koji (Department of Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Fujii Hiroshi (Graduate School of Science and Technology, Department of Biomedical Engineering, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Fujii Hiroshi (Department of Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Makabe Hidefumi (Graduate School of Agriculture, Sciences of Functional Foods, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Makabe Hidefumi (Graduate School of Science and Technology, Department of Agriculture, Division of Food Science and Biotechnology, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan) ,  Makabe Hidefumi (Department of Interdisciplinary Cluster for Cutting Edge Research, Shinshu University, 8304 Minami-minowa Kami-ina, Nagano, 399-4598, Japan)
Material： Tetrahedron  (Tetrahedron Symposia-in-Print)
Volume： 74  Issue： 27  Page： 3534-3542  Publication year： 2018 
JST Material Number： E0234A  ISSN： 0040-4020  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Syntheses of epigallocatechin ...

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Thesaurus term： electrophilic reagent ,  dimer ,  cell proliferation ,  *tumor ,  *Lewis acid ,  chemical synthesis ,  *antitumor action ,  monomer ,  *condensation reaction ,  nucleophilic reagent ,  *trimer ,  polyphenol ,  oxygen heterocyclic compound ,  flavonoid ,  polynuclear aromatic compound ,  polyol
Semi thesaurus term： PC-3細胞 ,  前立腺癌細胞 , 【Automatic Indexing@JST】

Author keywords (5)： Polyphenol ,  Condensation ,  Lewis acid ,  Proanthocyanidin ,  Antitumor

JST classification (1)： Condensed derivatives of pyrane  (CF07093I)

Substance index (3)： Pyrogallol ,  Catechin ,  Proanthocyanidin

Terms in the title (9)： Lewis酸 ,  ポット ,  縮合 ,  エピガロカテキン ,  三量体 ,  エピカテキン ,  カテキン ,  前立腺癌細胞 ,  抗腫瘍活性