Art

J-GLOBAL ID：201802280771242086   Reference number：18A0379841

Stability Orders of Acetaminophen and Theophylline Co-crystals Determined by Co-crystal Former Exchange Reactions and Their Correlation With In Silico and Thermal Parameters

共結晶旧交換反応により決定したアセトアミノフェンとテオフィリン共結晶の安定性順序とin silico及び熱的パラメータとの相関【Powered by NICT】

Author (4)： Mukaida Makoto (Asahi Kasei Pharma Corporation, Shizuoka 410-2321, Japan) ,  Sato Haruna (Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Toho University, Funabashi, Chiba 274-8510, Japan) ,  Sugano Kiyohiko (Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Toho University, Funabashi, Chiba 274-8510, Japan) ,  Terada Katsuhide (Laboratory of Molecular Pharmaceutics and Technology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki-shi, Gunma 370-0033, Japan)
Material： Journal of Pharmaceutical Sciences  (J Pharm Sci)
Volume： 106  Issue： 1  Page： 258-263  Publication year： 2017 
JST Material Number： C0260B  ISSN： 0022-3549  CODEN： JPMSAE  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The aim of this study was to d...

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Thesaurus term： solid phase ,  thermodynamic stability ,  *crystal ,  hydrogen bond ,  physical chemistry ,  ACTH ,  melting point ,  decomposition temperature ,  crystal structure ,  *exchange reaction ,  *co-crystal ,  phase (thermodynamics) ,  aliphatic carboxylic acid ,  olefin compound ,  unsaturated carboxylic acid ,  dicarboxylic acid ,  lactam ,  urea compound ,  fatty acid ,  aromatic amine ,  phenolic compound ,  carboxamide ,  aminoalcohol

Author keywords (6)： co-crystals ,  crystal engineering ,  crystal structure ,  physicochemical ,  solid state ,  stability

JST classification (2)： Physical pharmacy  (GY01012A) ,  Physicochemical characteristics of drugs  (GV01060M)

Substance index (4)： Maleic acid ,  Oxalic Acid ,  Theophylline ,  Acetaminophen

Terms in the title (8)： 共結晶 ,  交換反応 ,  アセトアミノフェン ,  テオフィリン ,  安定性 ,  順序 ,  パラメータ ,  相関