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J-GLOBAL ID：201802281214052316   Reference number：18A1295530

Cleavage of Toll-Like Receptor 9 Ectodomain Is Required for In Vivo Responses to Single Strand DNA

Toll様受容体9エクトドメインの切断は一本鎖DNAに対するin vivo応答に必要である【JST・京大機械翻訳】

Author (14)： Fukui Ryutaro (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Yamamoto Chikako (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Matsumoto Fumi (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Onji Masahiro (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Onji Masahiro (Institute of Molecular Biotechnology of the Austrian Academy of Sciences) ,  Shibata Takuma (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Murakami Yusuke (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Murakami Yusuke (Department of Pharmacotherapy, Research Institute of Pharmaceutical Sciences, Musashino University) ,  Kanno Atsuo (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Hayashi Takuto (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Tanimura Natsuko (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Yoshida Nobuaki (Laboratory of Developmental Genetics, The Institute of Medical Science, The University of Tokyo) ,  Miyake Kensuke (Division of Innate Immunity, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo) ,  Miyake Kensuke (Laboratory of Innate Immunity, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo)
Material： Frontiers in Immunology (Web)
Volume： 9  Page： 1491  Publication year： 2018 
JST Material Number： U7074A  ISSN： 1664-3224  Document type： Article
Article type： 原著論文  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Mouse toll-like receptor 9 (TL...

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Thesaurus term： dimerization ,  biochemistry ,  dendritic cell ,  endoplasmic reticulum ,  chemokine ,  transmembrane protein ,  *single-stranded DNA ,  gene ,  deletion mutation ,  proteolysis ,  inflammatory cytokine ,  in vitro experiment
Semi thesaurus term： リガンド ,  *ドメイン構造 ,  *エクトドメイン , 【Automatic Indexing@JST】

Author keywords (6)： toll-like receptor 9 ,  proteolytic cleavage ,  Unc93 homolog B1 ,  CpG-ODN ,  primary immune cells ,  in vivo response

JST classification (3)： Immunological reaction in general  (ED03010T) ,  Cell physiology in general  (EF02010S) ,  Receptors on cell membrane  (EF04030C)

Terms in the title (4)： Toll様受容体9 ,  エクトドメイン ,  一本鎖DNA ,  応答