Art

J-GLOBAL ID：201802281308808304   Reference number：18A0115713

Preparation and biological activities of anti-HER2 monoclonal antibodies with fully core-fucosylated homogeneous bi-antennary complex-type glycans

完全コアフコシル化均質的二分岐複合型グリカンを有する抗HER2モノクローナル抗体の調製および生物学的活性

Author (8)： TSUKIMURA Wataru (Noguchi Inst., Tokyo, JPN) ,  KUROGOCHI Masaki (Noguchi Inst., Tokyo, JPN) ,  MORI Masako (Noguchi Inst., Tokyo, JPN) ,  OSUMI Kenji (Noguchi Inst., Tokyo, JPN) ,  MATSUDA Akio (Noguchi Inst., Tokyo, JPN) ,  TAKEGAWA Kaoru (Kyushu Univ., Fukuoka, JPN) ,  FURUKAWA Kiyoshi (Noguchi Inst., Tokyo, JPN) ,  SHIRAI Takashi (Noguchi Inst., Tokyo, JPN)
Material： Bioscience, Biotechnology, and Biochemistry  (Bioscience Biotechnology & Biochemistry)
Volume： 81  Issue： 12  Page： 2353-2359  Publication year： Dec. 2017 
JST Material Number： G0021A  ISSN： 0916-8451  CODEN： BBBIEJ  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *monoclonal antibody ,...
Semi thesaurus term： *HER-2

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JST classification (3)： Production and application of antigens,antibodies,complements  (ED04030W) ,  Basic research of antitumor(=antineoplastic)drugs  (GW16010A) ,  Experimental treatment for tumors  (GE02040Y)

Reference (37)：

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• Ishii T, Ishida T, Utsunomiya A, et al. Defucosylated humanized anti-CCR4 monoclonal antibody KW-0761 as a novel immunotherapeutic agent for adult t-cell leukemia/lymphoma. Clin Cancer Res. 2010;16:1520-1531.
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Terms in the title (9)： コア ,  フコシル化 ,  分岐 ,  複合型 ,  グリカン ,  HER2 ,  モノクローナル抗体 ,  調製 ,  生物学的活性