Art

J-GLOBAL ID：201802283291771527   Reference number：18A0081573

Caveolin-1, a binding protein of CD26, is essential for the anti-inflammatory effects of dipeptidyl peptidase-4 inhibitors on human and mouse macrophages

カベオリン-1,CD26の結合蛋白質,はヒトおよびマウスのマクロファージに対するジペプチジルペプチダーゼ-4阻害剤の抗炎症効果に必須である【Powered by NICT】

Author (8)： Hiromura Munenori (Department of Internal Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan) ,  Nohtomi Kyoko (Department of Internal Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan) ,  Mori Yusaku (Department of Internal Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan) ,  Kataoka Hideo (Department of Oral Microbiology and Immunology, School of Dentistry, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan) ,  Sugano Marika (Department of Periodontology, Showa University School of Dentistry, 2-1-1 Kitasenzoku Ohta-ku, 145-8515, Tokyo, Japan) ,  Ohnuma Kei (Department of Therapy Development and Innovation for Immune Disorders and Cancers, Graduate School of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, 113-8421, Tokyo, Japan) ,  Kuwata Hirotaka (Department of Oral Microbiology and Immunology, School of Dentistry, Showa University, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan) ,  Hirano Tsutomu (Department of Internal Medicine, Division of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, 142-8555, Tokyo, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 495  Issue： 1  Page： 223-229  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： We previously reported that in...

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Thesaurus term： *inflammation ,  *human(primates) ,  phosphorylation ,  RT-PCR ,  lipopolysaccharide ,  Escherichia coli ,  transfection ,  cell membrane ,  siRNA ,  Toll like receptor ,  *anti-inflammatory action ,  *protein
Semi thesaurus term： Toll様受容体4 ,  *ジペプチジルペプチダーゼ4 , 【Automatic Indexing@JST】

Author keywords (6)： Caveolin-1 ,  CD26 ,  Dipeptidyl peptidase-4 inhibitor ,  Macrophage ,  Pro-inflammatory cytokine ,  Toll-like receptor (TLR)4

JST classification (3)： Basic research of anti-inflammatory drugs  (GW15010T) ,  Plant biochemistry  (EH01050J) ,  Gene expression  (EC02040Q)

Substance index (1)： Teneligliptin

Terms in the title (8)： カベオリン-1 ,  CD26 ,  結合蛋白質 ,  ヒト ,  マウス ,  マクロファージ ,  ジペプチジルペプチダーゼ-4阻害剤 ,  抗炎症効果