Art

J-GLOBAL ID：201802284935029127   Reference number：18A0081603

Identification of a selective inhibitor of human monocarboxylate transporter 4

ヒトモノカルボン酸輸送体4の選択的阻害剤の同定【Powered by NICT】

Author (7)： Futagi Yuya (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo 060-0812, Japan) ,  Futagi Yuya (Research Fellow of the Japan Society for the Promotion of Science (JSPS), 5-3-1 Kojimachi, Chiyoda-ku, Tokyo 102-0083, Japan) ,  Kobayashi Masaki (Department of Pharmacy, Hokkaido University Hospital, Kita-14-jo, Nishi-5-chome, Kita-ku, Sapporo 060-8648, Japan) ,  Narumi Katsuya (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo 060-0812, Japan) ,  Furugen Ayako (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo 060-0812, Japan) ,  Iseki Ken (Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo 060-0812, Japan) ,  Iseki Ken (Department of Pharmacy, Hokkaido University Hospital, Kita-14-jo, Nishi-5-chome, Kita-ku, Sapporo 060-8648, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 495  Issue： 1  Page： 427-432  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The human monocarboxylate tran...

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Thesaurus term： antitumor drug ,  pharmacology ,  energy metabolism ,  ovocyte ,  Xenopus laevis ,  cell membrane ,  oxygen deficiency ,  *human(primates) ,  tumor cell ,  fatty acid
Semi thesaurus term： *輸送体 ,  アイソフォーム ,  *阻害剤 ,  *モノカルボン酸輸送体 , 【Automatic Indexing@JST】

Author keywords (5)： Monocarboxylate transporter ,  hMCT1 ,  hMCT4 ,  Lactic acid ,  Oocyte

JST classification (3)： Basic research of enzyme preparations and enzyme inhibitor preparations  (GW21010W) ,  Enzyme in general  (EB09010D) ,  Function of cell components  (EF03060C)

Substance index (2)： Isobutyric acid ,  L-Lactic acid

Terms in the title (4)： ヒト ,  モノカルボン酸輸送体 ,  阻害剤 ,  同定