Art

J-GLOBAL ID：201802285249850715   Reference number：18A0996306

Carnosic acid attenuates cartilage degeneration through induction of heme oxygenase-1 in human articular chondrocytes

カルノシン酸はヒト関節軟骨細胞におけるヘムオキシゲナーゼ-1の誘導を介して軟骨変性を減弱する【JST・京大機械翻訳】

Author (14)： Ishitobi Hiroyuki (Department of Regenerative Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Ishitobi Hiroyuki (Department of Orthopaedic Surgery, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Sanada Yohei (Department of Regenerative Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Sanada Yohei (Department of Orthopaedic Surgery, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Kato Yoshio (Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan) ,  Ikuta Yasunari (Department of Orthopaedic Surgery, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Ikuta Yasunari (Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA) ,  Shibata Sachi (Department of Human Life Science Education, Graduate School of Education, Hiroshima University, 1-1-1 Higashi-Hiroshima, Hiroshima 739-8524, Japan) ,  Yamasaki Satoshi (Department of Rheumatology, Hiroshima University Hospital, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Lotz Martin K. (Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA) ,  Matsubara Kiminori (Department of Human Life Science Education, Graduate School of Education, Hiroshima University, 1-1-1 Higashi-Hiroshima, Hiroshima 739-8524, Japan) ,  Miyaki Shigeru (Department of Regenerative Medicine, Medical Center for Translational and Clinical Research, Hiroshima University Hospital, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Miyaki Shigeru (Department of Orthopaedic Surgery, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan) ,  Adachi Nobuo (Department of Orthopaedic Surgery, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan)
Material： European Journal of Pharmacology  (Eur J Pharmacol)
Volume： 830  Page： 1-8  Publication year： 2018 
JST Material Number： B0841A  ISSN： 0014-2999  CODEN： EJPHAZ  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Osteoarthritis (OA) is common ...

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Thesaurus term： down-regulation ,  dietary supplement ,  senile change ,  calcium ,  in vitro experiment ,  pathogenesis ,  osteoarthrosis ,  oxidation ,  up-regulation ,  *cartilage ,  *human(primates) ,  *heme oxygenase
Semi thesaurus term： miR-140 ,  動物モデル ,  *軟骨変性 , 【Automatic Indexing@JST】

Author keywords (5)： OA ,  HO-1 ,  CA ,  MiR-140 ,  BACH1

JST classification (2)： Transport of cell membrane  (EF04020R) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D)

Terms in the title (7)： カルノシン酸 ,  ヒト ,  関節軟骨細胞 ,  ヘムオキシゲナーゼ-1 ,  誘導 ,  軟骨変性 ,  減弱